Results 71 to 80 of about 5,165,384 (312)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Pneumonia in patients with cirrhosis: risk factors associated with mortality and predictive value of prognostic models

Respiratory Research, 2018
Background Cirrhosis always goes with profound immunity compromise, and makes those patients easily be the target of pneumonia. Cirrhotic patients with pneumonia have a dramatically increased mortality.
Lichen Xu, Shuangwei Ying, Jianhua Hu, Yunyun Wang, Meifang Yang, Tiantian Ge, Chunhong Huang, Qiaomai Xu, Haihong Zhu, Zhi Chen, Weihang Ma   +10 more
doaj   +1 more source

Survey on antibiotic regimens for necrotizing enterocolitis prescribed by Chinese pediatricians in 2020

World Journal of Pediatric Surgery, 2021
Background Necrotizing enterocolitis (NEC) is a serious intestinal inflammatory disease in neonates, and intravenous antibiotics constitute the main therapeutic strategy.
Yu He, Yuan Shi, Luquan Li, Zhongyao Zhang, Zhengli Wang, Lei Bao   +5 more
doaj   +1 more source

Sarcopenia from mechanism to diagnosis and treatment in liver disease [PDF]

, 2016
Sarcopenia or loss of skeletal muscle mass is the major component of malnutrition and is a frequent complication in cirrhosis that adversely affects clinical outcomes.
Dasarathy, Srinivasan, MERLI, Manuela
core   +1 more source

A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support. [PDF]

, 2020
Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of
Dunn, Steven P, Fallon, Julianne M, Kennedy, Jamie LW, Parker, Alex M   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Assessment of the Calibration of Periodontal Diagnosis and Treatment Planning Among Dental Students at Three Dental Schools [PDF]

, 2015
Calibration in diagnosis and treatment planning is difficult to achieve due to variations that exist in clinical interpretation. To determine if dental faculty members are consistent in teaching how to diagnose and treat periodontal disease, variations ...
Blanchard, Steven, Chaves, Eros, Eckert, George J., John, Vanchit, Lane, Brittany A., Luepke, Paul G., Maupome, Gerard   +6 more
core   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Construction of an immune-related gene signature to predict survival and treatment outcome in gastric cancer

Science Progress, 2021
Immune cells have emerged as key regulators in the occurrence and development of multiple tumor types. However, it is unclear whether immune-related genes (IRGs) and the tumor immune microenvironment can predict prognosis for patients with gastric cancer
Shuairan Zhang, Zhi Li, Hang Dong, Peihong Wu, Yang Liu, Tianshu Guo, Ce Li, Shuo Wang, Xiujuan Qu, Yunpeng Liu, Xiaofang Che, Ling Xu   +11 more
doaj   +1 more source

Migraine: Diagnosis, treatment and understanding c1960-2010 [PDF]

, 2014
seminar transcriptThere are around eight million migraine sufferers in the UK today. This Witness Seminar looked at the last 50 years of research into the diagnosis and treatment of the condition and the changing attitudes of the medical profession ...
Overy, C, Tansey, EM
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