Results 51 to 60 of about 3,700,007 (305)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Using Community-Owned Resource Persons to Provide Early Diagnosis and Treatment and Estimate Malaria Burden at Community Level in North-Eastern Tanzania. [PDF]

, 2012
Although early diagnosis and prompt treatment is an important strategy for control of malaria, using fever to initiate presumptive treatment with expensive artemisinin combination therapy is a major challenge; particularly in areas with declining burden ...
Martha M Lemnge, Mmbando Bruno P, Lemnge Martha M, Sembuche Samwel H, Kamugisha, Mathias L, Deus S Ishengoma, Johari Y Sadi, Bruno P Mmbando, Ezekiel K Malecela, Francis Filbert, Samwel H Sembuche, Kamugisha Mathias L, Acleus S M Rutta, Ishengoma Deus S, Ishengoma, Deus S, Mmbando, Bruno P, Malecela, Ezekiel K, Lemnge, Martha M, Sadi Johari Y, Sadi, Johari Y, Sembuche, Samwel H, Francis, Filbert, Rutta, Acleus S M, Rutta Acleus S M, Mathias L Kamugisha, Filbert Francis, Malecela Ezekiel K   +26 more
core   +1 more source

Clinical characteristics and outcomes during a severe influenza season in China during 2017–2018

BMC Infectious Diseases, 2019
Background A severe seasonal influenza epidemic was observed during 2017–2018 in China, prompting questions on clinical characteristics and outcomes of severe cases with influenza.
Xiaofang Fu, Yuqing Zhou, Jie Wu, Xiaoxiao Liu, Cheng Ding, Chenyang Huang, Shufa Zheng, Dhanasekaran Vijaykrishna, Yu Chen, Lanjuan Li, Shigui Yang   +10 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Pneumonia in patients with cirrhosis: risk factors associated with mortality and predictive value of prognostic models

Respiratory Research, 2018
Background Cirrhosis always goes with profound immunity compromise, and makes those patients easily be the target of pneumonia. Cirrhotic patients with pneumonia have a dramatically increased mortality.
Lichen Xu, Shuangwei Ying, Jianhua Hu, Yunyun Wang, Meifang Yang, Tiantian Ge, Chunhong Huang, Qiaomai Xu, Haihong Zhu, Zhi Chen, Weihang Ma   +10 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Impact of route to diagnosis on treatment intent and 1-year survival in patients diagnosed with oesophagogastric cancer in England: a prospective cohort study. [PDF]

, 2013
OBJECTIVE: To investigate the relationship between the route to diagnosis, patient characteristics, treatment intent and 1 -year survival among patients with oesophagogastric (O-G) cancer.
Cromwell, David A, Hardwick, Richard H, Riley, Stuart A, van der Meulen, Jan HP, Palser, Thomas R, Greenaway, Kimberley, National Oesophago-Gastric Cancer Audit   +6 more
core   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Chronic lymphocytic leukaemia: Up-dated recommendations on diagnosis and treatment [PDF]

, 2004
Diagnosis and treatment of chronic lymphatic leukaemia (CLL) are currently undergoing great change. New knowledge of prognosis factors and the numerous new therapeutic procedures now available, such as purine analogues, high-dose treatment and monoclonal
Hallek, M., Emmerich, B., Bergmann, M.
core   +1 more source

Theexpert consensus for the diagnosis and treatment of chronic kidney disease with hepatitis C infection

Linchuang shenzangbing zazhi, 2019
慢性肾脏病（chronic kidney disease,CKD）是我国重要的公共健康问题,流行率约10.8%,据此推算,我国成人CKD患者约1.2亿[1]。根据肾小球滤过率（estimated glomerular filtration rate,eGFR）,CKD可分为1～5期[2]。CKD患者免疫功能低下,易受细菌、病毒及其他病原体感染,而血液透析患者更是丙型肝炎病毒（hepatitis C virus,HCV）感染的高危人群 ...
The committee of expert consensus for the diagnosis and treatment of chronic kidney disease with hepatitis Cinfection
doaj