Results 131 to 140 of about 2,850,943 (269)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Barriers to the diagnosis and treatment of tuberculosis in Abidjan, Côte d'Ivoire: a qualitative study. [PDF]

open access: yesBMC Public Health
Benzekri NA   +10 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Bidirectional Relationship Between Systemic Immune-Inflammation Index and Postoperative Pneumonia in Elderly Patients Undergoing Colorectal Cancer Surgery: A Retrospective Cohort Study

open access: yesClinical Interventions in Aging
Yanmin Wu,1,* Bing Ye,1,* Tiantian Zhao,1,* Peihua Lu2 1Digestive Disease Diagnosis and Treatment Center, Affiliated Hospital of Jiangnan University, Wuxi, People’s Republic of China; 2Department of Oncology, The Affiliated Wuxi ...
Wu Y, Ye B, Zhao T, Lu P
doaj  

Splenomegaly. ? Diagnosis and Treatment [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1928
openaire   +2 more sources

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