Results 131 to 140 of about 3,700,007 (305)
Alcohol-Related Brain Damage (ARBD) - diagnosis and treatment.
Alcohol-related brain damage can be hard to diagnose, in part because of the confusion it causes for people with the condition.
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Objective To examine the characteristics and spatiotemporal changes in the phenotypes and genotypes of extended-spectrum β-lactamases (ESBLs) in Escherichia coli strains isolated from bloodstream infections (BSIs) across China between 2014 and 2021 ...
Sayyed Salman +5 more
doaj +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Hodgkin’s lymphoma in adults – diagnosis and treatment
Hodgkin’s lymphoma (HL) is a malignant disease of the lymphatic system with two peaks of incidence. Often one of the first symptoms of the disease is non-painful enlargement of the lymph nodes.
Dagmara Jabłońska +4 more
core +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The global prevalence of preterm labor (PL) is 6-12%. Despite the large number of studies focused on exploring the options for diagnosis and prevention of PL, there are currently no methods of absolute diagnostic or prognostic value. Methods.
Olga V. Mikheeva
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Vulvar varicosities: diagnosis, treatment, and prevention
Sergey G Gavrilov Faculty of Medicine, Pirogov Russian National Research Medical University, Moscow, Russia Objective: Vulvar varicosity is a relatively common venous disorder in women with varicose veins of the pelvis and lower extremities and in ...
Gavrilov SG
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