Results 111 to 120 of about 986,235 (292)

Theoretical study of the X-ray emission from astrophysical shock waves [PDF]

open access: yes
Theoretical X-ray emission spectra are needed to interpret the X-ray emission observed by many low and moderate resolution X-ray instruments, and to provide diagnosis of physical conditions for high resolution spectra.
Raymond, J.
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Protocol for development of a reporting guideline (TRIPOD-Code) for code repositories associated with diagnostic and prognostic prediction model studies

open access: yesDiagnostic and Prognostic Research
Introduction The Transparent Reporting of a multivariable prediction model of Individual Prognosis Or Diagnosis (TRIPOD) statement was published to improve the reporting and critical appraisal of prediction model studies for diagnosis and prognosis. This
Tom Pollard   +8 more
doaj   +1 more source

Hip Arthroscopy After Total Hip Arthroplasty Is Rare (0.04%) and May be Contralateral

open access: yesArthroscopy, Sports Medicine, and Rehabilitation
Purpose: To determine the patient demographics and incidence of hip arthroscopy after total hip arthroplasty using the PearlDiver database. Methods: This is a retrospective study of patients undergoing total hip arthroplasty and arthroscopic hip surgery.
Caitlin A. Orner, M.D.   +1 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Positive Predictive Value of ICD-10 Codes for Identifying Hypocalcemia in Women with Postmenopausal Osteoporosis in Swedish Patient Register: A Validation Study

open access: yesClinical Epidemiology
Anders Kjellman,1 Min Kim,2 Per-Olof Lundgren,1 Tomas Thiel,1 Anna Thor,1 Helena Thulin,1 David Hägg,3 Vera Ehrenstein4 1Urology Department, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden; 2Center for Observational Research ...
Kjellman A   +7 more
doaj  

Techniques for improving reliability of computers [PDF]

open access: yes, 1972
Modular design techniques improve methods of error detection, diagnosis, and recovery. Theoretical computer (MARCS (Modular Architecture for Reliable Computer Systems)) study deals with postulated and modeled technology indigenous to 1975-1980.
Bouricius, W. G.   +5 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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