Results 201 to 210 of about 4,179,888 (309)

Paget-Schrotter Syndrome in the Primary Care Setting: A Case Report and Scoping Review of Clinical Presentation and Diagnostic Delay. [PDF]

Clin Pract
Hteit M, Ghazvinian R, Abdulrasak M.
europepmc   +1 more source

A diagnostic revolution [PDF]

Tidsskrift for Den norske legeforening, 2013
openaire   +2 more sources

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Estimating total human deaths from rabies: A statistical framework leveraging reports of rabies transmission from deceased organ and tissue donors. [PDF]

PLoS Negl Trop Dis
Kim Y, Chen J, Yan A, Alrefae T, Bajaj S, Donnelly CA.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

An Integrated Analysis of Manganese Metabolism-Related Genes and Their Association With Biomarkers, Immune Infiltration, and Clinical Subtypes in Alzheimer's Disease. [PDF]

Genes Brain Behav
Shu S, Hu J, Hu S, Yao Y.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Maintaining quality out-of-hours in an acute cardiology service in a UK primary PCI centre. [PDF]

Open Heart
Shaw C, Roberts K, McDonagh K, Frosdick A, Thomas M, Robson F, Jose L, Moore K, Williams D, Hetherington S, Ehtisham J, El-Din M, Raju P, Farooq M, Helal A.   +14 more
europepmc   +1 more source

Diagnostic performance of fine needle aspiration cytology in the preoperative identification of mucoepidermoid carcinoma: a cross-sectional diagnostic analytical study. [PDF]

J Pathol Transl Med
Sumaya, Sonuwane DR, Krishnappa A.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source