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CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification. [PDF]

open access: yesJ Extracell Vesicles
Zhang H   +19 more
europepmc   +1 more source
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Diagnostic biomarkers in multiple sclerosis

Expert Opinion on Medical Diagnostics, 2007
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the CNS and comprises a heterogeneous spectrum of disease subtypes. The distinctive variability of clinical presentations, histopathologic and immunologic patterns, as well as neuroradiologic phenotypes in MS poses a diagnostic challenge to the attending physician and claims a ...
Bettina, Kuenz   +3 more
openaire   +2 more sources

Diagnostic biomarkers of diabetic nephropathy

Expert Opinion on Medical Diagnostics, 2008
Clinical management and therapeutic intervention from the earlier stage of diabetic nephropathy (DN) is of major importance to prevent the progression of DN to end stage renal disease. At present, the measurement of albuminuria is used as a standardized non-invasive test for the diagnosis of early DN.
Hideyuki, Ito   +2 more
openaire   +2 more sources

Diagnostic biomarkers of prostate cancer

Scandinavian Journal of Urology and Nephrology, 2010
Diagnostic tissue biomarkers for prostate cancer (PC) include basal cell markers and α-methylacyl-coenzyme A-racemase (AMACR), often used in combination. Their sensitivity and specificity are not perfect and there is a need for additional diagnostic biomarkers for PC in cases that are difficult to diagnose on routine stained sections.This study ...
Häggarth L   +6 more
openaire   +3 more sources

Biomarker rediscovery in diagnostics

Expert Opinion on Medical Diagnostics, 2008
Proteomics has evolved into a large-scale biomarker discovery program; however, these initiatives are viewed as failing owing to a lack of successful implementation of new protein biomarkers in the diagnostic arena. New approaches to proteomics biomarker discovery and validation may be the key to boosting clinical proteomics into diagnostics.To review ...
openaire   +2 more sources

Molecular diagnostics and biomarkers in cholangiocarcinoma

Surgical Oncology, 2022
Regardless of anatomic origin, cholangiocarcinoma is generally an aggressive malignancy with a relatively high case fatality. Surgical resection with curative intent remains the best opportunity to achieve meaningful long-term survival. Most patients present, however, with advanced disease and less than 20% of patients are candidates for surgical ...
Zachary J. Brown   +3 more
openaire   +2 more sources

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