Results 1 to 10 of about 295,913 (316)
PLoS ONE, 2020 Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as
Si Cheng +5 more
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An appraisal of studies using mouse models to assist the biomarker discovery for sepsis prognosis
Heliyon, 2023 Introduction: Clinicians need reliable outcome predictors to improve the prognosis of septic patients. Mouse models are widely used in sepsis research. We aimed to review how mouse models were used to search for novel prognostic biomarkers of sepsis in ...
Yaqing Jiao +2 more
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BMC Cancer, 2021 Background Liver cancer is the sixth most commonly diagnosed cancer and the fourth most common cause of cancer death. The purpose of this work is to find new diagnostic biomarkers or prognostic biomarkers and explore the biological functions related to ...
Shiyong Gao +4 more
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Gene signature for prognosis in comparison of pancreatic cancer patients with diabetes and non-diabetes [PDF]
PeerJ, 2020 Background Pancreatic cancer (PC) has much weaker prognosis, which can be divided into diabetes and non-diabetes. PC patients with diabetes mellitus will have more opportunities for physical examination due to diabetes, while pancreatic cancer patients ...
Mingjun Yang +5 more
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The Roles of Exosomes as Future Therapeutic Agents and Diagnostic Tools for Glioma
Frontiers in Oncology, 2021 Glioma is a common type of tumor originating in the brain. Glioma develops in the gluey supporting cells (glial cells) that surround and support nerve cells.
Xiaoben Wu +7 more
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Overexpressing PTTG family genes predict poor prognosis in kidney renal clear cell carcinoma
World Journal of Surgical Oncology, 2021 Background Pituitary tumor transforming genes (PTTG1, PTTG2, and PTTG3P) play key roles in the pathogenesis and development of human cancers. The studies show that overexpression of the PTTG genes is associated with tumor progression and migration ...
Yonghui Gui +3 more
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BMC Cancer, 2021 Background In the phase 3 METEOR trial, cabozantinib improved progression-free survival (PFS) and overall survival (OS) versus everolimus in patients with advanced RCC after prior antiangiogenic therapy.
Thomas Powles +12 more
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Molecular Markers in Guiding Lung Cancer Diagnosis and Treatment
Journal of Men's Health, 2022 Background: Lung cancer has the highest mortality rates and one of the lowest 5-year survival rates amongst cancer types in the world. Although there are constant advancements in treatment, the overall prognosis for lung cancer continues to be poor.
Vivian Li, Wickii T. Vigneswaran
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The Journal of Pathology: Clinical Research, 2021 Immune cell infiltration has been identified as a prognostic biomarker in several cancers. However, no immune based biomarker has yet been validated for use in pancreatic ductal adenocarcinoma (PDAC). We undertook a systematic review and meta‐analysis of
Andrew J McGuigan +6 more
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A Combined Long Noncoding RNA Signature as a Candidate Prognostic Biomarker for Ovarian Cancer
Frontiers in Oncology, 2021 AimsDysregulated long noncoding RNAs (lncRNAs) contributing to ovarian cancer (OC) development may serve as prognostic biomarker. We aimed to explore a lncRNA signature to serve as prognostic biomarker of OC.MethodsUnivariate Cox regression was conducted
Hui Li +13 more
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