Results 31 to 40 of about 295,913 (316)

Prognostic Value of Colorectal Cancer Biomarkers [PDF]

Cancers, 2011
Despite the large amount of data in cancer biology and many studies into the likely survival of colorectal cancer (CRC) patients, knowledge regarding the issue of CRC prognostic biomarkers remains poor. The Tumor-Node-Metastasis (TNM) staging system continues to be the most powerful and reliable predictor of the clinical outcome of CRC patients.
P. Bianchi, L. Laghi, G. Delconte, A. Malesci   +3 more
openaire   +3 more sources

Evolving Insights Into the Biological Function and Clinical Significance of Long Noncoding RNA in Glioblastoma

Frontiers in Cell and Developmental Biology, 2022
Glioblastoma (GBM) is one of the most prevalent and aggressive cancers worldwide. The overall survival period of GBM patients is only 15 months even with standard combination therapy.
Kun Liu, Hong Chen, Yuanyuan Wang, Liping Jiang, Liping Jiang, Yi Li   +5 more
doaj   +1 more source

Identification of Potential Diagnostic and Prognostic Biomarkers for Colorectal Cancer Based on GEO and TCGA Databases

Frontiers in Genetics, 2021
Colorectal cancer (CRC) is one of the most common neoplastic diseases worldwide. With a high recurrence rate among all cancers, treatment of CRC only improved a little over the last two decades.
Zhenjiang Wang, Mingyi Guo, Xinbo Ai, Jianbin Cheng, Zaiwei Huang, Xiaobin Li, Yuping Chen   +6 more
doaj   +1 more source

Response to “prognostic biomarkers in oral leukoplakia” [PDF]

Oral Diseases, 2019
We thank Professor Warnakulasuriya for his letter (Warnakulasuriya, 2019) and comments in relation to our systematic review of prospective studies assessing the prognostic biomarkers of oral leukoplakia (Villa et al., 2019). We agree that identifying prognostic biomarkers for oral leukoplakia is an important topic for oral medicine specialists.
Alessandro Villa, Antonio Celentano, Ingrid Glurich, Wenche S. Borgnakke, Siri Beier Jensen, Douglas E. Peterson, Konstantina Delli, David Ojeda, Arjan Vissink, Camile S. Farah   +9 more
openaire   +4 more sources

CSPG4 as a prognostic biomarker in chordoma

The Spine Journal, 2016
There are currently no generally accepted biomarkers used in the clinical treatment of chordoma tumors. CSPG4 has been associated with disease severity in other tumors.This study aimed to characterize the frequency of CSPG4 expression in chordoma tumors and to correlate it with disease severity and clinical outcome.A retrospective review of clinical ...
Andrew J, Schoenfeld, Xinhui, Wang, Yangyang, Wang, Francis J, Hornicek, G Petur, Nielsen, Zhenfeng, Duan, Soldano, Ferrone, Joseph H, Schwab   +7 more
openaire   +3 more sources

Adrenomedullin Is a Diagnostic and Prognostic Biomarker for Acute Intracerebral Hemorrhage [PDF]

, 2021
Hemorrhagic stroke remains an important health challenge. Adrenomedullin (AM) is a vasoactive peptide with an important role in cardiovascular diseases, including stroke. Serum AM and nitrate–nitrite and S-nitroso compounds (NOx) levels were measured and
Alfredo Martínez, Esther Martínez-Lara, Eva Siles, Martínez, Alfredo [0000-0003-4882-4044], Francisco J. Julián-Villaverde, Ochoa-Callejero, Laura [0000-0001-5366-6613], Martínez, Alfredo, Siles, Eva [0000-0003-4192-7008], Siles, Eva, Laura Ochoa-Callejero, Martínez-Lara, Esther, Ochoa-Callejero, Laura, Martínez-Lara, Esther [0000-0002-4962-3634], Julián-Villaverde, Francisco J.   +13 more
core   +1 more source

MMP2 as an independent prognostic stratifier in oral cavity cancers

OncoImmunology, 2020
Background Around 25% of oral cavity squamous cell carcinoma (OCSCC) are not controlled by the standard of care, but there is currently no validated biomarker to identify those patients. Our objective was to determine a robust biomarker for severe OCSCC,
Caroline Hoffmann, Sophie Vacher, Philémon Sirven, Charlotte Lecerf, Lucile Massenet, Aurélie Moreira, Aurore Surun, Anne Schnitzler, Jerzy Klijanienko, Odette Mariani, Emmanuelle Jeannot, Nathalie Badois, Maria Lesnik, Olivier Choussy, Christophe Le Tourneau, Maude Guillot-Delost, Maud Kamal, Ivan Bieche, Vassili Soumelis   +18 more
doaj   +1 more source

Circulating Fibroblast Growth Factor 21 (Fgf21) as Diagnostic and Prognostic Biomarker in Renal Cancer [PDF]

, 2016
Background: The finding of new biomarkers is needed to have a better sub-classification of primary renal tumors (RCC) as well as more reliable predictors of outcome and therapy response.
Knott, María Elena, Minatta, J.N, Roulet, L., De Lorenzo, M, Gueglio G., Ranuncolo, Stella Maris, Nuñez, M, Pasik, Leonardo, Puricelli, Lydia Ines   +8 more
core   +1 more source

High EVI1 and PARP1 expression as favourable prognostic markers in high-grade serous ovarian carcinoma

Journal of Ovarian Research, 2023
Background Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are upregulated in cancers with DNA repair deficiencies with DNA repair deficiencies and may ...
Paul Jank, Jonas Leichsenring, Svenja Kolb, Inga Hoffmann, Philip Bischoff, Catarina Alisa Kunze, Mihnea P. Dragomir, Moritz Gleitsmann, Moritz Jesinghaus, Wolfgang D. Schmitt, Hagen Kulbe, Christine Sers, Albrecht Stenzinger, Jalid Sehouli, Ioana Elena Braicu, Christina Westhoff, David Horst, Carsten Denkert, Stefan Gröschel, Eliane T. Taube   +19 more
doaj   +1 more source

Diagnostic and prognostic biomarkers for HAND

Journal of NeuroVirology, 2019
In 2007, the nosology for HIV-1-associated neurocognitive disorders (HAND) was updated to a primarily neurocognitive disorder. However, currently available diagnostic tools lack the sensitivity and specificity needed for an accurate diagnosis for HAND. Scientists and clinicians, therefore, have been on a quest for an innovative biomarker to diagnose (i.
Kristen A, McLaurin, Rosemarie M, Booze, Charles F, Mactutus   +2 more
openaire   +3 more sources