Results 21 to 30 of about 409,524 (305)

Effects of Rivaroxaban on Biomarkers of Coagulation and Inflammation: A Post Hoc Analysis of the X-VeRT Trial. [PDF]

, 2020
Introduction  This X-VeRT (eXplore the efficacy and safety of once-daily oral riVaroxaban for the prevention of caRdiovascular events in patients with nonvalvular aTrial fibrillation scheduled for cardioversion) substudy evaluated the effects of ...
Camm, AJ, Cappato, R, Ezekowitz, MD, Hohnloser, SH, Kirchhof, P, Meng, IL, Purmah, Y, Schiffer, S, Schulz, A, Wosnitza, M   +9 more
core   +1 more source

Diagnostic and prognostic accuracy of Protein C in adult patients with sepsis: protocol for a systematic review and meta-analysis

BMJ Open, 2021
Introduction Sepsis is a dysregulated host response to infection characterised by activation of proinflammatory and procoagulant mechanisms. Protein C (PC)’s activity as an anticoagulant and antiinflammatory molecule makes it an appealing target for ...
Alison Fox-Robichaud, Fatima Sheikh, Kush Patel, Vanessa Catenacci   +3 more
doaj   +1 more source

Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study. [PDF]

, 2017
Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus ...
Baeten, Kurt, Connelly, Mark C, D'Haese, David, Flynt, Amy, Gross, Steve, McCleod, Michael, Morano, Carrie, Peek, Victoria L, Polzer, John, Raddad, Eyas, Repollet, Madeline, Roberson, Stephanie, Salgia, Ravi, Sanders, Renouard, Spigel, David R, Stille, John R, Um, Suzane L, Weaver, R Waide, Wijayawardana, Sameera R, Yan, S Betty   +19 more
core   +1 more source

suPAR as a prognostic biomarker in sepsis [PDF]

BMC Medicine, 2012
Abstract Sepsis is the clinical syndrome derived from the host response to an infection and severe sepsis is the leading cause of death in critically ill patients. Several biomarkers have been tested for use in diagnosis and prognostication in patients with sepsis.
DONADELLO, Katia, Scolletta, Sabino, COVAJES, Cecilia, Vincent, Jean Louis   +3 more
openaire   +7 more sources

A simulation study on estimating biomarker–treatment interaction effects in randomized trials with prognostic variables

Trials, 2018
Background To individualize treatment decisions based on patient characteristics, identification of an interaction between a biomarker and treatment is necessary.
Bernhard Haller, Kurt Ulm
doaj   +1 more source

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma [PDF]

, 2015
Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers.
, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Cannoodt, Robrecht, Clément, Nathalie, Combaret, Valérie, De Preter, Katleen, De Wilde, Bram, Decock, Anneleen, Haber, Michelle, Hoyoux, Claire, Laureys, Geneviève, Murray, Jayne, Noguera, Rosa, Ongenaert, Maté, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Speleman, Frank, Stallings, Ray L., Tweddle, Deborah A., Van Roy, Nadine, Vandesompele, Jo, Verniers, Kimberly   +24 more
core   +2 more sources

Prognostic impact of autophagy biomarkers for cutaneous melanoma.

Frontiers in Oncology, 2016
Prognosis and survival for malignant melanoma is highly dependent on early diagnosis and treatment. While the American Joint Committee on Cancer (AJCC) criteria provides a means of staging melanomas and guiding treatment approaches, it is unable to ...
Diana Yao Li Tang, Robert Ellis, Robert Ellis, Penny Lovat   +3 more
doaj   +1 more source

Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]

, 2016
Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core   +2 more sources

Identification of a prognostic biomarker predicting biochemical recurrence and construction of a novel nomogram for prostate cancer

Frontiers in Oncology, 2023
BackgroundBiochemical recurrence (BCR) is common in prostate cancer (PCa), but its prediction is based predominantly on clinicopathological characteristics with low accuracy.
Zhaojun Yu, Zhaojun Yu, Haichao Chao, Fanghua Xu, Huanhuan Deng, Huanhuan Deng, Leihong Deng, Zhen Song, Tao Zeng   +8 more
doaj   +1 more source

Diagnostic and prognostic biomarkers in cholangiocarcinoma [PDF]

Liver International, 2019
AbstractThe high mortality rate of cholangiocarcinoma (CCA) is due, in part, to the lack of non‐invasive approaches able to accurately detect this silent tumour at early stages, when therapeutic options can be potentially curative or may at least increase the overall survival of patients.
Macias, Rocio I. R., Kornek, Miroslaw, Rodrigues, Pedro M., Paiva, Nuno A., Castro, Rui E., Urban, Sabine, Pereira, Stephen P., Cadamuro, Massimiliano, Rupp, Christian, Loosen, Sven H., Luedde, Tom, Banales, Jesus M.   +11 more
openaire   +4 more sources