Results 271 to 280 of about 518,832 (292)
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Exosomes and diagnostic biomarkers
2023The invention provides methods for the detection of M. tuberculosis proteins in or on exosomes derived from infected individuals. The methods can use a proteomic approach including mass spectroscopy, data mining and multiplex reaction monitoring to quickly examine a large amount of M.
Schorey, Jeffrey S., Dobos, Karen M.
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Diagnostic mesothelioma biomarkers in effusion cytology
Cancer Cytopathology, 2021Malignant mesothelioma is a rare malignancy with a poor prognosis whose development is related to asbestos fiber exposure. An increasing role of genetic predisposition has been recognized recently. Pleural biopsy is the gold standard for diagnosis, in which the identification of pleural invasion by atypical mesothelial cell is a major criterion ...
Albino Eccher +5 more
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Neuroimaging: Diagnostic Boundaries and Biomarkers
2019Different medical disciplines have adopted biomarkers in order to establish a diagnosis and predict clinical and functional outcome of a disease. In psychiatry, the search for biomarkers could lead to substantial improvement in mental disorder diagnosis and care.
Galderisi S. +2 more
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MicroRNAs: Biomarkers, Diagnostics, and Therapeutics
2017MicroRNAs (miRNAs) are small noncoding RNAs (21-23 nucleotides in length) that regulate gene expression at translational or posttranslational levels. The major regulatory mechanisms include translational repression or mRNA degradation (Filipowicz et al., Curr Opin Struct Biol 15:331-341, 2005).Aberrant expression of miRNAs has been found to be ...
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Diagnostic biomarkers for lung cancer prevention
Journal of Breath Research, 2018Lung cancer is the leading cause of death for neoplasm. Lung cancer mortality is frequently associated with late diagnosis, therefore an early diagnosis is a key factor to significantly improve overall survival in high risk populations of asymptomatic patients.
Roberto Gasparri +7 more
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Salivary biomarkers for periodontal disease diagnostics
Expert Opinion on Medical Diagnostics, 2010Periodontal disease is one of the most prevalent of all diseases. The chronic inflammatory process causes tooth loss and is associated with negative systemic effects. There are still major challenges when it comes to precise diagnosis, prognosis and appropriate disease therapy.
Ole, Brinkmann +3 more
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Tumour biomarkers: diagnostic, prognostic, and predictive:
BMJ, 2015A 63 year old woman presented with a one month history of difficulty speaking and imbalance. She had been diagnosed with breast cancer two years earlier and had been treated with surgery, chemotherapy, and radiotherapy. This was followed by a year of trastuzumab (Herceptin) and continuous tamoxifen treatment.
Shaw, Abigail +3 more
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Diagnostic work up: Laboratory and biomarkers
2022This chapter will focus on the diagnostic work around sexual dysfunction in Parkinson's disease, especially laboratory tests and biomarkers. A number of methods to analyze if sexual dysfunction is caused by neural pathology, vascular dysfunction or other mechanisms are now available.
Gustav, Cedergren Weber, Per, Odin
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Biosensors for biomarkers in medical diagnostics
Biomarkers, 2008At present, most biomarker testing is taking place at centralised dedicated laboratories using large, automated analysers, increasing waiting time and costs. Smaller, faster and cheaper devices are highly desired for replacing these time-consuming laboratory analyses and for making analytical results available at the patient's bedside (point-of-care ...
MASCINI, MARCO, TOMBELLI, SARA
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Epigenetic biomarkers in colorectal cancer diagnostics
Expert Review of Molecular Diagnostics, 2012Colorectal cancer (CRC) is a significant health burden worldwide. Despite advancements in treatment options, improvements in CRC patient survival have been limited owing to lack of early detection and limited capacity for optimal therapeutic decision-making.
James B, Rawson, Bharati, Bapat
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