The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Case Report: Sustained biochemical remission following early initiation of odevixibat in an infant with monoallelic ABCB11 mutation and histologically confirmed PFIC2. [PDF]
Kehler T +6 more
europepmc +1 more source
Vitamin D levels and biomarkers of male fecundity: A study from the Danish National Birth Cohort
Abstract Background Vitamin D is metabolised throughout the male reproductive system, suggesting a direct regulatory role of vitamin D in male reproduction. Objectives To investigate the association between plasma vitamin D levels at sperm ejaculation and during spermatogenesis and biomarkers of male fecundity in young men.
Anne Gaml‐Sørensen +8 more
wiley +1 more source
Lateral lymph node dissection combined with endoscopic submucosal dissection for early rectal cancer complicated with ulcerative colitis: A case report. [PDF]
Huang B, Zhu B, Liu R, Ren B.
europepmc +1 more source
Abstract This paper explores the relationship between wetland ecosystems and prehistoric lakeshore settlements within the Lake Ohrid basin (a biodiversity hotspot) by considering plant food systems at Ploča Mičov Grad, North Macedonia. The mid‐fifth millennium (c.4555–4373 to 4437–4241 cal BCE) waterlogged assemblage contained a diverse spectrum of ...
Amy Holguin +14 more
wiley +1 more source
Yield of next-generation sequencing in diagnostic work up of suspicious biliary strictures
Tina L. N. Meijering +7 more
doaj +1 more source
Single catheter strategy for transradial angiography and primary percutaneous coronary intervention enhances procedural efficiency, microvascular outcomes, and cost-effectiveness: Implications for STEMI healthcare in resource-limited settings. [PDF]
Arneja M +12 more
europepmc +1 more source
The Provenance of Silver in the Viking‐Age Hoard From Bedale, North Yorkshire
ABSTRACT The acquisition of silver was a key motive propelling the Viking expansion out of Scandinavia; identifying the sources of Viking silver during the early part of the Viking Age can provide critical insights into the relative significance of western European and eastern, Islamic wealth in the Viking expansion.
Jane Kershaw +5 more
wiley +1 more source
Digitizing Dignity: Analyzing Digital Twins Through the Lens of Multidimensional Human Dignity
ABSTRACT In precision medicine, digital twins—virtual models of patients created using personalized data and advanced machine learning—are potentially changing healthcare by predicting health outcomes and guiding medical decisions. However, their use raises complex ethical questions, particularly concerning their relationship to human dignity. Patients
Andrew J. Barnhart
wiley +1 more source
Effects of woody plant encroachment on abundance of multiple tick species in the U.S. Great Plains. [PDF]
Propst J, Taylor T, Loss SR, Noden BH.
europepmc +1 more source

