Results 141 to 150 of about 360,735 (260)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers. [PDF]

Acad Emerg Med
Mahajan P, White E, Shaw K, Parker SJ, Chamberlain J, Ruddy RM, Alpern ER, Corboy J, Krack A, Ku B, Morrison Ponce D, Payne AS, Freiheit E, Horvath G, Kolenic G, Carney M, Klekowski N, O'Connell KJ, Singh H.   +18 more
europepmc   +1 more source

Aberrant expression of cytokeratin in plasma cell neoplasms: A pitfall for diagnostic errors. [PDF]

EJHaem, 2022
Huang M, Sakhdari A.
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Autopsy rates and diagnostic errors in a Swiss community hospital: a ten-year retrospective analysis. [PDF]

Virchows Arch
Hagen CM, Eriksson U, Schmid K, Flury R, Bode PK.   +4 more
europepmc   +1 more source

Vestibular syndromes, diagnosis and diagnostic errors in patients with dizziness presenting to the emergency department: a cross-sectional study. [PDF]

BMJ Open, 2023
Comolli L, Korda A, Zamaro E, Wagner F, Sauter TC, Caversaccio MD, Nikles F, Jung S, Mantokoudis G.   +8 more
europepmc   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records From an Integrated Health System

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the frequency and timing of physician referrals to physical therapists (PTs) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

Types of diagnostic errors reported by paediatric emergency providers in a global paediatric emergency care research network. [PDF]

BMJ Open Qual, 2023
Mahajan P, Grubenhoff JA, Cranford J, Bhatt M, Chamberlain JM, Chang T, Lyttle M, Oostenbrink R, Roland D, Rudy RM, Shaw KN, Zuniga RV, Belle A, Kuppermann N, Singh H.   +14 more
europepmc   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source