Results 71 to 80 of about 853,706 (301)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

CADASIL vs. Multiple Sclerosis: Is It Misdiagnosis or Concomitant? A Case Series

Frontiers in Neurology, 2020
Introduction: Cerebral autosomal dominant arteriopathy and subcortical infarct leukoencephalopathy (CADASIL) is the most common form of hereditary stroke caused by a mutation in the NOTCH3 gene located on the short arm of chromosome 19. A small number of
Ayesha Khan, Vida Abedi, Vida Abedi, Jiang Li, Muhammad T. Malik, Megan Esch, Ramin Zand, Ramin Zand   +7 more
doaj   +1 more source

Analysis of the Rate of Discrepancy between Preliminary Reports by Radiology Residents and Final Reports by Certified Radiologists for Emergency Radiology: Studies in a University Hospital

대한영상의학회지, 2021
Purpose In the adult emergency department of a university hospital, we investigated the frequency of major discrepancies between the preliminary reports by radiology residents and the final reports by certified radiologists.
Younbeom Jeong, Cheong-Il Shin, Hwan Jun Jae, Jung Hoon Kim, Jin Wook Chung   +4 more
doaj   +1 more source

Why Are People's Decisions Sometimes Worse with Computer Support? [PDF]

, 2009
In many applications of computerised decision support, a recognised source of undesired outcomes is operators' apparent over-reliance on automation. For instance, an operator may fail to react to a potentially dangerous situation because a computer fails
A.M. Bisantz, A.R. Pritchett, B. Azar, B. Latanedo, B.M. Muir, B.M. Muir, B.M. Muir, E. Alberdi, E. Alberdi, E. Alberdi, I. Dassonville, I.L. Singh, I.L. Singh, J. Meyer, J. Meyer, J.D. Lee, J.E. Bahner, J.P. Bliss, K.L. Mosier, L. Bainbridge, L. Strigini, L.J. Skitka, L.J. Skitka, M.T. Dzindolet, M.T. Dzindolet, N. Moray, P. Vries de, R. Parasuraman, R. Parasuraman, R. Parasuraman, R.D. Sorkin, S.J. Karau   +31 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Misdiagnosis and Quality of Management in Paediatric Surgical Patients Referred to a Tertiary Care Hospital [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: The literature on diagnosis and management prior to transfer paediatric surgical patients to a tertiary care center is scarce. In referral centers, it is common to receive patients previously subjected to inadequate or inappropriate health
Eduardo Bracho-Blanchet, Joel Cazares-Rangel, Cristian Zalles-Vidal, Roberto Davila-Perez   +3 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Determining diagnostic delays in Romanian multiple myeloma patients using the Aarhus statement

Frontiers in Medicine
IntroductionMultiple Myeloma (MM) is classified as one of the most challenging cancers to diagnose, and the hematological malignancy is associated with prolonged diagnostic delays.
Ruxandra Irimia, Sorina Badelita, Sinziana Barbu, Sinziana Barbu, Ioana Loredana Cirlan, Larisa Zidaru, Daniel Coriu, Daniel Coriu   +7 more
doaj   +1 more source

A mathematical framework for combining decisions of multiple experts toward accurate and remote diagnosis of malaria using tele-microscopy. [PDF]

, 2012
We propose a methodology for digitally fusing diagnostic decisions made by multiple medical experts in order to improve accuracy of diagnosis. Toward this goal, we report an experimental study involving nine experts, where each one was given more than 8 ...
Dimitrov, Stoyan, Feng, Steve, Mavandadi, Sam, Nielsen-Saines, Karin, Ozcan, Aydogan, Prescott, William R, Yu, Frank   +6 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source