Results 71 to 80 of about 390,338 (298)

Collaborative Diagnostic Conversations Between Clinicians, Patients, and Their Families: A Way to Avoid Diagnostic Errors

, 2023
Objective: To identify the components of the collaborative diagnostic conversations between clinicians, patients, and their families and how deficiencies in these conversations can lead to diagnostic errors.
Nataly R. Espinoza Suarez, MD, Naykky Singh Ospina, MD, MSc, Juan P. Brito, MD, MSc, Angela Sivly, Ian Hargraves, PhD, Andrew Majka, MD   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A determination and classification of student errors in lower-level calculus through computer-aided assessment and analysis

, 2011
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.This thesis describes the determination of student errors through paper-based assessment through to computer-aided assessment.
Hanson, James
core  

Developing a Questionnaire to Investigate Monthly Human Errors Among Railway Traffic Control Room Employees [PDF]

Iranian Rehabilitation Journal
Objectives: The working situation of railway traffic control rooms (RTCR) employees makes them susceptible to human error. On the other hand, the occurrence of human error by these staff can lead to catastrophic events.
Soleiman Ramezanifar, Ali Askari, Mohsen Porsadeghin, Mahshid Namdari, Ali Salehi Sahlabadi   +4 more
doaj  

Determining diagnostic delays in Romanian multiple myeloma patients using the Aarhus statement

Frontiers in Medicine
IntroductionMultiple Myeloma (MM) is classified as one of the most challenging cancers to diagnose, and the hematological malignancy is associated with prolonged diagnostic delays.
Ruxandra Irimia, Sorina Badelita, Sinziana Barbu, Sinziana Barbu, Ioana Loredana Cirlan, Larisa Zidaru, Daniel Coriu, Daniel Coriu   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

War games and diagnostic errors

, 2016
From the 1940s to the 1990s the United States and the former Soviet Union (USSR) confronted each other in a cold war. Each side feared and distrusted the other. Each side was prepared to respond to an attack with immediate nuclear retaliation.
Chopra, V, Howell, JD, Vaughn, VM
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Modelling of errors in databases

, 2008
A lot of time and energy are expended assembling national databases containing information about health care processes and outcomes. Unfortunately, given the complexity of the data gathering procedures involved, errors occur.
Gallivan, S., Pagel, C.
core  

Metabolic Evaluation of Epilepsy: A Diagnostic Algorithm With Focus on Treatable Conditions: A Diagnostic Algorithm With Focus on Treatable Conditions [PDF]

, 2018
Although inborn errors of metabolism do not represent the most common cause of seizures, their early identification is of utmost importance, since many will require therapeutic measures beyond that of common anti-epileptic drugs, either in order to ...
Nenad Blau, Carlos R. Ferreira, Horvath, Gabriella A, Bryan Sayson, Horvath, Gabriella A., Carlos R. Ferreira (6035918), Jessica J. Y. Lee, van Karnebeek, Clara D M, van Karnebeek, Clara D. M., Nenad Blau (3664690), Tseng, Laura A, Sayson, Bryan, Gabriella A. Horvath, Bryan Sayson (6035906), Gabriella A. Horvath (6035915), Ferreira, Carlos R, Ferreira, Carlos R., Clara D. M. van Karnebeek, Clara D. M. van Karnebeek (6035903), Lee, Jessica J Y, Lee, Jessica J. Y., Tseng, Laura A., Blau, Nenad, Jessica J. Y. Lee (6035909), Laura A. Tseng (6035912), Laura A. Tseng   +25 more
core   +1 more source