Results 91 to 100 of about 1,030,441 (312)

Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome

open access: yes, 2013
Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM   +15 more
core   +1 more source

Comparison of the main diagnostic features of the described species.

open access: yes, 2020
Comparison of the main diagnostic features of the described species.
Grzegorz J. Wolski (8561769)   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Interpretation of radiomics features–A pictorial review

open access: yes, 2022
Radiomics is a newcomer field that has opened new windows for precision medicine. It is related to extraction of a large number of quantitative features from medical images, which may be difficult to detect visually.
Bureau, Nathalie J   +3 more
core   +1 more source

Features of immunohistochemical diagnostic of melanocytic tumours.

open access: yesMorphologia, 2013
Background. The malignant melanomas are the most important group of skin cancers. Although less common than the familiar basal and squamous cell tumours of the skin, they are much more frequently fatal, due to their intrinsic tendency to lymphatic and haematogenic metastasis. Objective.
Shpon’ka, I. S.   +4 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diagnostic Features of English-Lexifier Creoles: a new look at Bahamian [PDF]

open access: yesBucharest Working Papers in Linguistics, 2013
This paper is a partial replica of a study by Hackert and Huber (2007). It first documents the earliest attestations in Bahamian of the diagnostic features of English-lexifier pidgins and creoles proposed by Baker and Huber (2001).
Andrei A. Avram
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models. [PDF]

open access: yes, 2010
BACKGROUND: Culture remains the diagnostic gold standard for many bacterial infections, and the method against which other tests are often evaluated.
Lisa J White   +58 more
core   +1 more source

Home - About - Disclaimer - Privacy