Results 131 to 140 of about 6,677,261 (309)

Deficit schizophrenia is a discrete diagnostic category defined by neuro-immune and neurocognitive features: results of supervised machine learning

, 2023
Deficit schizophrenia is a discrete diagnostic category defined by neuro-immune and neurocognitive features: results of supervised machine ...
S Thika (13330878), B Kanchanatawan (13330695), A F Carvalho (13330368), Michael Maes (13055841), M Geffard (13330701), M Kubera (13330200), S Sirivichayakul (13330596), S Sriswasdi (13330365)   +7 more
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Fine-needle aspiration cytology diagnosis of a symptomatic bony metastasis from an occult hepatocellular carcinoma: a case report.

, 1990
Fine-needle aspiration cytology is widely used for rapid diagnosis. We here report a case in which aspiration of a mass in the left posterior aspect of the chest wall in an elderly patient revealed metastasis from a clinically unrecognized hepatocellular
Ho, JW, Ng, IO, Leung, CY
core   +1 more source

Ranking of diagnostic features of childhood pulmonary tuberculosis by medical doctors in southeastern Nigeria

Nigerian Journal of Paediatrics
Objective: To rank diagnostic features of childhood pulmonary tuberculosis; and to determine the effect of working in tuberculosis Directly Observed Treatment Short Course (DOTS) facilities on the ranking of these features by medical doctors. Methods:
Nnaji GA , Chukwu JN, Ezechukwu CC , Ugochukwu EF, Ogbonnaya LU, Ogbuabor DC   +5 more
doaj  

STFF-CANet Diagnosis Model of Aero-Engine Surge Based on Spatio-Temporal Feature Fusion

Aerospace
Aero engine surge diagnosis is a key technology in engine health management, and its diagnostic accuracy is of great significance for ensuring operational safety.
Chunyan Hu, Yafeng Shen, Qingwen Zeng, Gang Xu, Jiaxian Sun, Keqiang Miao   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Diagnostic features of English-lexifier contact-languages: Grenada Creole English [PDF]

, 2014
This paper draws on both diachronic and synchronic data and presents the attestations in Grenada Creole English of the diagnostic features of English-lexifier pidgins and creoles proposed by Baker & Huber (2001).
Avram, Andrei A.
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source