The accurate diagnosis of sleep disorders requires an electroencephalography (EEG) recording. However, in-home EEG-based sleep monitoring has been hindered by the present cumbersome electrode systems which are impractical for patient self-application. To
Laura Kalevo+7 more
doaj +1 more source
A machine learning approach for differentiating malignant from benign enhancing foci on breast MRI
Background Differentiate malignant from benign enhancing foci on breast magnetic resonance imaging (MRI) through radiomic signature. Methods Forty-five enhancing foci in 45 patients were included in this retrospective study, with needle biopsy or imaging
Natascha C. D’Amico+10 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Radiation dose optimisation in paediatric head CT using attenuation-based auto prescription
Minimizing ionizing radiation is crucial in paediatric imaging due to children’s increased radiation sensitivity, especially at younger ages. To evaluate a CT attenuation-based Auto Prescription protocol for paediatric head imaging, testing whether it ...
Michael Zellner+6 more
doaj +1 more source
Onset of granulomatosis with polyangiitis obscured by heart disease in an elderly man
We describe a case of 85-year-old man who presented to the Emergency Department with sudden dyspnea. He had a past medical history of cardiomyopathy and radiography and nonenhanced computed tomography (CT) of the chest showed pulmonary edema.
C. Pace+4 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker+9 more
wiley +1 more source
Load matters: neural correlates of verbal working memory in children with autism spectrum disorder
Background Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterised by diminished social reciprocity and communication skills and the presence of stereotyped and restricted behaviours.
Vanessa M. Vogan+4 more
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Alternative gel based material red seaweed for ultrasonography examination
Background: Red seaweed extract of kappa and iota carrageenan is commonly used as a gel base. Kappa carrageenan is stiffed or breakable that may experience syneresis.
Sudiyono SE. M. Kes+8 more
doaj
Patent Urachus Presenting as Acute Abdomen
The urachus is an epithelial tubular structure located in the midline that spreads from the anterosuperior part of the bladder to the navel, connecting the apex of the urinary bladder with the allantois in the fetus, and is involved in forming the ...
Mauro de Queiroz Garcia+2 more
doaj +1 more source