Results 171 to 180 of about 75,801 (290)

Adaptive diagnostic reasoning framework for pathology with multimodal large language models. [PDF]

Commun Med (Lond)
Hong Y, Kao KC, Edwards L, Liu NT, Huang CY, Oliveira-Kowaleski A, Hsieh CJ, Lin NYC.   +7 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Language-Specific Differences in Large Language Model Diagnostic Reasoning: A Translation-Controlled Clinical Vignette Study. [PDF]

J Clin Med
Ibrahim-El-Nur JM, Kaczmarek W, Winiarska W, Kuś A, Łoś M.   +4 more
europepmc   +1 more source

Emulating Clinical Diagnostic Reasoning for Jaw Cysts with Machine Learning. [PDF]

Diagnostics (Basel), 2022
Feher B, Kuchler U, Schwendicke F, Schneider L, Cejudo Grano de Oro JE, Xi T, Vinayahalingam S, Hsu TH, Brinz J, Chaurasia A, Dhingra K, Gaudin RA, Mohammad-Rahimi H, Pereira N, Perez-Pastor F, Tryfonos O, Uribe SE, Hanisch M, Krois J.   +18 more
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Black Balls and Diagnostic Reasoning

Academic Medicine, 2012
Jonathan, Sherbino, Geoff, Norman
openaire   +3 more sources

Beyond Binary Cutoffs: An Explainable Machine Learning Framework for Individualized Diagnostic Reasoning in Suspected Urolithiasis. [PDF]

Diagnostics (Basel)
Cha K, Oh SH, Shin J, Lim JY.
europepmc   +1 more source

An analysis of physicians' diagnostic reasoning regarding pediatric abusive head trauma. [PDF]

Child Abuse Negl, 2022
Hymel KP, Boos SC, Armijo-Garcia V, Musick M, Weeks K, Haney SB, Marinello M, Herman BE, Frazier TN, Carroll CL, Even K, Wang M, Pediatric Brain Injury Research Network (PediBIRN) Investigators.   +12 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source