Results 171 to 180 of about 1,862,073 (282)

Immunoglobulin G4 (IgG4)-Related Disease With a Biphasic Clinical Course of Spontaneous Remission and Relapse: A Case Report of Diagnostic Reasoning. [PDF]

Cureus
Kidogawa H, Okimoto T, Fukudome Y, Noguchi J, Yamayoshi T.   +4 more
europepmc   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Adaptive diagnostic reasoning framework for pathology with multimodal large language models. [PDF]

Commun Med (Lond)
Hong Y, Kao KC, Edwards L, Liu NT, Huang CY, Oliveira-Kowaleski A, Hsieh CJ, Lin NYC.   +7 more
europepmc   +1 more source

Reasoning on Rounds: a Framework for Teaching Diagnostic Reasoning in the Inpatient Setting. [PDF]

J Gen Intern Med, 2023
Penner JC, Shipley LC, Minter DJ.
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Multi-Task Training with In-Domain Language Models for Diagnostic Reasoning. [PDF]

Proc Conf Assoc Comput Linguist Meet, 2023
Sharma B, Gao Y, Miller T, Churpek MM, Afshar M, Dligach D.   +5 more
europepmc   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Beyond accuracy metrics: Toward responsible integration of large language models in pediatric diagnostic reasoning. [PDF]

Pediatr Investig
Mansoor M.
europepmc   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Chronic cerebrospinal fluid leak can cause amyotrophic lateral sclerosis mimic

Journal of General and Family Medicine
Satoshi Saito, Ryotaro Ikeguchi, Kazuo Kitagawa   +2 more
doaj   +1 more source