Results 151 to 160 of about 13,232,132 (369)

Object oriented fault diagnosis system for space shuttle main engine redlines [PDF]

open access: yes
A great deal of attention has recently been given to Artificial Intelligence research in the area of computer aided diagnostics. Due to the dynamic and complex nature of space shuttle red-line parameters, a research effort is under way to develop a real ...
Mohapatra, Saroj Kumar, Rogers, John S.
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Diagnostic molecular techniques in haematology: recent advances [PDF]

open access: hybrid, 2018
Aikaterini Koutsi   +1 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Advancements in MRI radiomics for hepatocellular carcinoma: a narrative review [PDF]

open access: yesJournal of Research in Applied and Basic Medical Sciences
Background & Aims: Hepatocellular carcinoma (HCC) is a major global health concern, ranking sixth among prevalent cancers worldwide and third in cancer-related deaths. Despite diagnostic advancements, prognosis remains challenging.
Sakarie Mustafe Hidig   +3 more
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Rheumato(Philes): A Publication Option for Rheumatology Devotees’ Creative Works

open access: yesRheumato
This journal for Rheumato(philes) has provided a vehicle for the interdisciplinary sharing of the challenges and interventions of our specialty. The provision of state-of-the-art information is not at the expense of the basics from which it has grown ...
Bruce M. Rothschild
doaj   +1 more source

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