Results 131 to 140 of about 1,729,034 (298)

Using output to evaluate and refine rules in rule-based expert systems [PDF]

The techniques described provide an effective tool which knowledge engineers and domain experts can utilize to help in evaluating and refining rules. These techniques have been used successfully as learning mechanisms in a prototype adaptive diagnostic ...
Bond, W. E., Flachsbart, B. B., St.clair, D. C.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Advancements in MRI radiomics for hepatocellular carcinoma: a narrative review [PDF]

Journal of Research in Applied and Basic Medical Sciences
Background & Aims: Hepatocellular carcinoma (HCC) is a major global health concern, ranking sixth among prevalent cancers worldwide and third in cancer-related deaths. Despite diagnostic advancements, prognosis remains challenging.
Sakarie Mustafe Hidig, Hannan Samtar, Fidele Kakule Kitaghenda, Mohamed Abdifatah Mohamed   +3 more
doaj  

Rheumato(Philes): A Publication Option for Rheumatology Devotees’ Creative Works

Rheumato
This journal for Rheumato(philes) has provided a vehicle for the interdisciplinary sharing of the challenges and interventions of our specialty. The provision of state-of-the-art information is not at the expense of the basics from which it has grown ...
Bruce M. Rothschild
doaj   +1 more source

Electro-optic bunch diagnostics on ALICE [PDF]

, 2009
An electro-optic longitudinal bunch profile monitor has been implemented on ALICE (Accelerators and Lasers in Combined Experiments) at the Daresbury Laboratories and will be used both to characterise the electron bunch and to provide a testbed for ...
Gillespie, W. A., Jamison, S. P., MacLeod, A. M., Phillips, P. J.   +3 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Longtitudinal electron beam diagnostics via upconversion of THz to visible radiation [PDF]

, 2009
Longitudinal electro-optic electron bunch diagnostics has been successfully applied at several accelerators. The electro-optic effect can be seen as an upconversion of the Coulomb field of the relativistic electron bunch (THz radiation) to the visible ...
Berden, G., Gillespie, W. A., Jamison, S. P., MacLeod, Allan M., Phillips, P. J., van der Meer, A. F. G.   +5 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Group Motivational Interviewing as a Psychotherapeutic Intervention for Dual Diagnosis Patients Living with a Psychotic Disorder: Critique of the Literature [PDF]

, 2012
Studies indicate that 50% of individuals living with a psychotic disorder also meet Diagnostic and Statistical Manual IV Text Revision (DSM-IV-TR) criteria for substance abuse disorder during their lifetime (Green, Drake, Brunette, & Noordsy, 2007 ...
Stauder, Alexander D
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source