Results 161 to 170 of about 9,461,475 (306)

Effect of Diagnostic Test Type on Detection of Salmonella Infections - Foodborne Diseases Active Surveillance Network, 2004-2024. [PDF]

MMWR Morb Mortal Wkly Rep
Tierney R, Louis RP, Boxrud DJ, Lamas KH, Angelo KM, Weller DL.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Diagnostic Accuracy of a Simple and Rapid Diagnostic Test RLDT for the Detection of Cholera in Bangladesh. [PDF]

Open Forum Infect Dis
Islam K, Khan AI, Bhuiyan MDTR, He F, Khan ZH, Islam MT, Qadri F, Chakraborty S.   +7 more
europepmc   +1 more source

Test Track; aerial view

Aerial view of the concrete tractor test track and east campus of the University of Nebraska-Lincoln looking toward the southeast.
Nebraska Tractor Test Laboratory
core  

test

, 2015
testtesttes
test, test
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Diagnostic Test Accuracy of Serum Glutamate Dehydrogenase (GLDH) for Drug-Induced Liver Injury: A Meta-Analysis. [PDF]

Cureus
Sarma I, Nath C, Ahmed KA, Rajkhowa P, Biswas KP, Saikia D.   +5 more
europepmc   +1 more source

test

, 2000
test
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source