Results 111 to 120 of about 1,354,199 (345)

Effect of screening abdominal ultrasound examination on the decision to pursue advanced diagnostic tests and treatment in dogs with neurologic disease. [PDF]

open access: yes, 2015
BackgroundAbdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis.ObjectivesDescribe the type and frequency of abnormalities found by AUS in ...
Blair, WH   +5 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Admission dental examination: protocol and its importance in the diagnosis of oral pathology

open access: yesBrazilian Journal of Oral Sciences, 2015
The aim of this paper is to describe an efficient clinical protocol used in admittance dental examinations, highlighting the importance of this evaluation in the diagnosis of oral pathologies.
Mário Marques Fernandes   +5 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Prostatic Acid Phosphatase: A Potpourri [PDF]

open access: yes, 1973
I would first like to discuss this enzyme, reviewing some of its chemistry, its clinical value and the pitfalls and problems associated with the routine tests.
Moncure, Charles W.
core   +1 more source

Time for change: a new training programme for morpho-molecular pathologists? [PDF]

open access: yes, 2018
The evolution of cellular pathology as a specialty has always been driven by technological developments and the clinical relevance of incorporating novel investigations into diagnostic practice.
Jones, J. Louise   +6 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Testing for ARCH in the Presence of Nonlinearity of Unknown Form in the Conditional Mean [PDF]

open access: yes
Tests of ARCH are a routine diagnostic in empirical econometric and financial analysis. However, it is well known that misspecification of the conditional mean may lead to spurious rejections of the null hypothesis of no ARCH.
Andrew P. Blake, George Kapetanios
core  

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

open access: yes, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari   +118 more
core   +2 more sources

The ethics of testing a test: randomized trials of the health impact of diagnostic tests for infectious diseases.

open access: yesClinical Infectious Diseases, 2012
In the last decade, many new rapid diagnostic tests for infectious diseases have been developed. In general, these new tests are developed with the intent to optimize feasibility and population health, not accuracy alone.
D. Dowdy   +5 more
semanticscholar   +1 more source

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