Results 111 to 120 of about 1,288,068 (341)

Performance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study

BMC Infectious Diseases
Background Limited literature exists on the diagnostic yield of traditional and molecular tuberculosis (TB) tests using bronchoalveolar lavage (BAL) specimens in high burden South American countries. The aim of the study is to determine the value of acid-
Vanessa Sabella-Jiménez, Valentina L. Sabella-Jiménez, Valentina Restrepo-Espinosa, Juanita Eljadue-Flórez, Claredit Valentina Gallardo-Castro, Andrea Alexandra Silvera, Carlos Otero-Herrera, Hugo Andrés Macareno Arroyo, Jorge Acosta-Reyes, Jorge Luis Quintero Barrios   +9 more
doaj   +1 more source

Willingness to use a rapid diagnostic test for malaria in a rural area of central Côte d'Ivoire [PDF]

, 2012
: BACKGROUND: Malaria mortality is mainly a direct consequence of inadequate and/or delayed diagnosis and case management. Some important control interventions (e.g.
Koudou, Benjamin, Raso, Giovanna, Tanner, M., Utzinger, Jürg, Ouattara Allassane F, Utzinger, J., Ouattara, Allassane F, Comoé, C. C., Raso, G., Tanner Marcel, Utzinger Jürg, Comoé Colombe Coffie, Koudou, B. G., Ouattara, A. F., Raso Giovanna, Koudou Benjamin G, Comoé, Colombe Coffie, Tanner, Marcel   +17 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Long read sequencing on its way to the routine diagnostics of genetic diseases

Frontiers in Genetics
The clinical application of technological progress in the identification of DNA alterations has always led to improvements of diagnostic yields in genetic medicine.
Giulia Olivucci, Emanuela Iovino, G. Innella, D. Turchetti, T. Pippucci, P. Magini   +5 more
semanticscholar   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Interim guidance for the detection of novel Influenza A virus using rapid influenza diagnostic tests [PDF]

This guidance was revised to clarify that the current rRT-PCR developed by CDC to detect novel influenza A ( H1N1) is authorized by the FDA. The FDA authorization, also termed Emergency Use Authorization or EUA, is not equivalent to FDA cleared, which ...

core  

Malaria Rapid Testing by Community Health Workers is Effective and Safe for Targeting Malaria Treatment: Randomised Cross-over Trial in Tanzania. [PDF]

, 2011
Early diagnosis and prompt, effective treatment of uncomplicated malaria is critical to prevent severe disease, death and malaria transmission. We assessed the impact of rapid malaria diagnostic tests (RDTs) by community health workers (CHWs) on ...
Petzold, M.G, Ka¨ llander, K., Max G. Petzold, Gustafsson, Lars L, Marian Warsame, Massele Amos, Källander, K,, Lars L Gustafsson, Gustafsson Lars L., Mubi, M., Massele, Amos, Max G Petzold, Premji, Z., Tomson, G, Björkman, Anders, Marycelina Mubi, Amos Massele, Premji, Zul, Ngasala Billy, Maganga, G., Karin Källander, Maganga, G,, Mubi, Marycelina, Anders Björkman, Warsame, M,, Warsame, M., Ngasala, Billy, Petzold Max G., Maganga, Gloria, Kallander, K., Björkman Anders, Zul Premji, Mårtensson, Andreas, Tomson, G., Martensson, A., Bjorkman, A., Ngasala, B., Mårtensson, A,, Petzold, Max G, Ngasala, B,, Göran Tomson, Tomson, Göran, Tomson Göran, Massele, A., Mårtensson Andreas, Lars L. Gustafsson, Massele, A,, Petzold, M.G., Bjo¨rkman, A., Janson, A,, Petzold, M.G,, Premji Zul, Maganga Gloria, Janson, A., Andreas Mårtensson, Gloria Maganga, Warsame, Marian, Gustafsson, L.L, Källander, Karin, Warsame Marian, Källander Karin, Mub, M., Janson Annika, Billy Ngasala, Janson, Annika, Mubi Marycelina, Gustafsson, L.L., Gustafsson, L.L,, Ma°rtensson, A., Annika Janson   +69 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Screening Performance Characteristic of Ultrasonography and Radiography in Detection of Pleural Effusion; a Meta-Analysis

Emergency, 2016
Introduction: The role of ultrasonography in detection of pleural effusion has long been a subject of interest but controversial results have been reported.
Mahmoud Yousefifard, Masoud Baikpour, Parisa Ghelichkhani, Hadi Asady, Kavous Shahsavari Nia, Ali Moghadas Jafari, Mostafa Hosseini, Saeed Safari   +7 more
doaj  

Frequency and indication of non-musculoskeletal examinations: a cross-sectional survey of Quebec chiropractors

Chiropractic & Manual Therapies
Background Approximately 1% of low back pain is estimated to be caused by serious systemic diseases, including cancer, infection, or abdominal aortic dissection.
Danikel Giroux, Chloé Branconnier, André Bussières, Jean Théroux, Marc-André Blanchette   +4 more
doaj   +1 more source