Results 121 to 130 of about 1,354,199 (345)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Performance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study

BMC Infectious Diseases
Background Limited literature exists on the diagnostic yield of traditional and molecular tuberculosis (TB) tests using bronchoalveolar lavage (BAL) specimens in high burden South American countries. The aim of the study is to determine the value of acid-
Vanessa Sabella-Jiménez, Valentina L. Sabella-Jiménez, Valentina Restrepo-Espinosa, Juanita Eljadue-Flórez, Claredit Valentina Gallardo-Castro, Andrea Alexandra Silvera, Carlos Otero-Herrera, Hugo Andrés Macareno Arroyo, Jorge Acosta-Reyes, Jorge Luis Quintero Barrios   +9 more
doaj   +1 more source

A randomised controlled trial to measure the effect of chest pain unit care upon anxiety, depression, and health-related quality of life [ISRCTN85078221] [PDF]

, 2004
Background The chest pain unit (CPU) has been developed to provide a rapid and accurate diagnostic assessment for patients attending hospital with acute, undifferentiated chest pain.
Goodacre, S., Nicholl, J.
core   +3 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Diagnostic issues and capabilities in 48 isolation facilities in 16 European countries: data from EuroNHID surveys [PDF]

, 2012
Background: Highly infectious diseases (HIDs) are defined as being transmissible from person to person, causing life-threatening illnesses and presenting a serious public health hazard. The sampling, handling and transport of specimens from patients with
Barbara Bannister, Francesco Fusco, Gail Thomson, Giuseppe Ippolito, Giuseppina De Iaco, Helen C Maltezou, null null, Philippe Brouqui, Reinhard H Brodt, Rene Gottschalk, Simon-Djamel Thiberville, Stefan Schilling, Vincenzo Puro   +12 more
core   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Screening Performance Characteristic of Ultrasonography and Radiography in Detection of Pleural Effusion; a Meta-Analysis

Emergency, 2016
Introduction: The role of ultrasonography in detection of pleural effusion has long been a subject of interest but controversial results have been reported.
Mahmoud Yousefifard, Masoud Baikpour, Parisa Ghelichkhani, Hadi Asady, Kavous Shahsavari Nia, Ali Moghadas Jafari, Mostafa Hosseini, Saeed Safari   +7 more
doaj  

Frequency and indication of non-musculoskeletal examinations: a cross-sectional survey of Quebec chiropractors

Chiropractic & Manual Therapies
Background Approximately 1% of low back pain is estimated to be caused by serious systemic diseases, including cancer, infection, or abdominal aortic dissection.
Danikel Giroux, Chloé Branconnier, André Bussières, Jean Théroux, Marc-André Blanchette   +4 more
doaj   +1 more source

Talking about routines in the field: the emergence of organizational capabilities in a new cellular phone network company [PDF]

, 1997
No abstract ...
Narduzzo, Alessandro, Rocco, Elena, Warglien, Massimo   +2 more
core  

Accuracy of Malaria Rapid Diagnostic Tests in Community Studies and their Impact on Treatment of Malaria in an Area with Declining Malaria Burden in North-Eastern Tanzania. [PDF]

, 2011
Despite some problems related to accuracy and applicability of malaria rapid diagnostic tests (RDTs), they are currently the best option in areas with limited laboratory services for improving case management through parasitological diagnosis and ...
A Enevold, A Laurent, A Moody, AB Ly, BP Mmbando, BP Mmbando, Bruno P Mmbando, C Sayang, CA Petti, CI Chandler, CK Murray, CM Zikusooka, D Bell, D Bell, D Bell, Deus S Ishengoma, DJ Kyabayinze, DJ Kyabayinze, DR Ishengoma, DR Ishengoma, EK Ansah, Filbert Francis, H Hopkins, H Reyburn, H Reyburn, I Bates, Ib C Bygbjerg, J Bendezu, J Chinkhumba, John PA Lusingu, JP Lusingu, JP Lusingu, M Alifrangis, Martha M Lemnge, MI Msellem, Michael Alifrangis, Ministry of Health, ML McMorrow, ML McMorrow, MM Lemnge, N Singh, P Mens, Pamela Magistrado, R Development Core Team. R, RN Bronzan, S Gerstl, TA Abeku, Thor G Theander, V Batwala, V D'Acremont, WHO, WHO, WP O'Meara, Z Bisoffi, Z Bisoffi   +54 more
core   +4 more sources