Results 51 to 60 of about 605,483 (283)

meta4diag: Bayesian Bivariate Meta-Analysis of Diagnostic Test Studies for Routine Practice [PDF]

Journal of Statistical Software, 2018
This paper introduces the \proglang{R} package \pkg{meta4diag} for implementing Bayesian bivariate meta-analyses of diagnostic test studies. Our package \pkg{meta4diag} is a purpose-built front end of the \proglang{R} package \pkg{INLA}. While \pkg{INLA} offers full Bayesian inference for the large set of latent Gaussian models using integrated nested ...
Guo, Jingyi, Riebler, Andrea Ingeborg
openaire   +6 more sources

Tumoral chromoblastomycosis: a rare manifestation with typical complementary exams [PDF]

Anais Brasileiros de Dermatologia, 2015
: Chromoblastomycosis is a chronic subcutaneous fungal infection caused by traumatic implantation of dematiaceous fungi in the skin. The clinical presentation is usually a verrucous plaque lesion and the diagnosis is confirmed by the visualization of ...
John Verrinder Veasey, Beatriz de Abreu Ribeiro Machado, Rute Facchini Lellis, Laura Hitomi Muramatu, Clarisse Zaitz   +4 more
doaj   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Diagnostic Accuracy of Optic Nerve Ultrasonography and Ophthalmoscopy in Prediction of Elevated Intracranial Pressure

Archives of Academic Emergency Medicine, 2018
Introduction: Elevated intracranial pressure (ICP) is a major and potentially lethal disorder in patients admitted to the emergency department (ED). Several methods are being used to investigate for elevated ICP.
Keihan Golshani, Mehdi Ebrahim zadeh, Ziba Farajzadegan, Fariborz Khorvash   +3 more
doaj   +1 more source

Emoqol-100: Development and validation of a single question for low mood in primary care. A retrospective audit.

BJGP Open, 2023
Background: Patients with depression need to be diagnosed and managed effectively in primary care. However, current inventories for case-finding low mood are time-consuming when considering the limited time available during appointments. Aim: To validate
Nina Edel Dahle, Carolyn Matthew, Rachel Petronella Roskvist, Fiona Moir, Bruce Arroll   +4 more
doaj   +1 more source

Community chloroquine distribution for malaria control in Bushenyi district of Uganda. [PDF]

, 2003
OBJECTIVE: To document successful community chloroquine distribution for malaria control in Bushenyi district, southwestern Uganda. DESIGN: A cross sectional survey immediately after a four-month community chloroquine distribution exercise.
Nuwaha, F, Okware, J, Timbyetaho, HN
core   +1 more source

Diagnostic value of routine exercise testing in hospital patients with angina pectoris. [PDF]

BMJ, 1979
A group of patients with angina pectoris were investigated prospectively using a simple and well-recognised exercise test protocol, and S-T segment displacements during exercise were correlated with the results of coronary arteriography. Definitive exercise results in 100 patients correlated well with findings on coronary angiograms: 69 out of 70 ...
I Y Luksic, D A S G Mary, J B Stoker, W. Whitaker, C T Kappagoda, J A Raffo, R J Linden   +6 more
openaire   +3 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Investigating rapid diagnostic testing in Kenya’s health system, 2018–2020: validating non-reporting in routine data using a health facility service assessment survey

BMC Health Services Research, 2023
Background Understanding the availability of rapid diagnostic tests (RDTs) is essential for attaining universal health care and reducing health inequalities.
Angela K Moturi, Bibian N Robert, Felix Bahati, Peter M Macharia, Emelda A Okiro   +4 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source