Results 71 to 80 of about 1,288,068 (341)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Proving Bone Marrow Plasma Cell Clonality by Flow Cytometry: An Important Tool in the Diagnosis of Immunoglobulin Light-Chain Amyloidosis

Biomedicines
Background/Objectives: Light-chain amyloidosis (AL Amyloidosis) is a rare systemic plasma cell disorder in which misfolded light chains form amyloid fibrils that damage vital organs. Diagnosis is often delayed because of variable presentation and overlap
Sorina Nicoleta Badelita, Horia Mihail Sandu, Daniel Coriu, Andreea Jercan, Sinziana Barbu, Larisa Zidaru, Mihai Emanuel Himcinschi, Camelia Dobrea, Monica Popescu, Delia Codruta Popa   +9 more
doaj   +1 more source

Ensemble learning model for diagnosing COVID-19 from routine blood tests

Informatics in Medicine Unlocked, 2020
Background and objectives: The pandemic of novel coronavirus disease 2019 (COVID-19) has severely impacted human society with a massive death toll worldwide.
Maryam AlJame, Imtiaz Ahmad, Ayyub Imtiaz, Ameer Mohammed   +3 more
doaj   +1 more source

Clinical comparison of three SARS-CoV-2 nucleic acid amplification tests for routine diagnostic testing

Heliyon, 2023
Background: Cycle threshold (Ct) values from SARS-CoV-2 nucleic acid amplification tests have been used to estimate viral load for treatment decisions.
Tetiana Garmatiuk, Christine Gränitz-Trisko, Charlotte Sochor-Geischläger, Theresa Polsterer, Francesca Caselotto, Lukas Willitsch, Birgit Reinhardt, Wolfgang Huf   +7 more
doaj   +1 more source

THE DIAGNOSTIC POTENTIAL OF SOME ROUTINE LABORATORY TESTS

International Journal of Clinical Practice, 1993
SUMMARY The potential was tested of white blood cell count (WBC), haemoglobin concentration (Hb) and erythrocyte volume fraction (EVF) to differentiate between patients with acute mesenteric ischaemia (AMI), perforation of colon, perforation of peptic ulcer, and intestinal obstruction.
E Bjørnestad, RT Lie, CW Janssen
openaire   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Novel electrodiagnostic provocative techniques for the diagnosis of suspected tarsal tunnel syndrome

Egyptian Rheumatology and Rehabilitation, 2022
Background Electrodiagnostic tests  (EDXTs) have been considered the gold standard method for the diagnosis of tarsal tunnel syndrome (TTS); however, definitive tests has not yet been discovered.
Mona M. Hasab ElNaby, Amr Farouk Abdel Rahman, Rehab Ali Ibrahim   +2 more
doaj   +1 more source

Effectiveness of professional and patient-oriented strategies in reducing vitamin D and B12 test ordering in primary care: a cluster randomised intervention study

BJGP Open, 2021
Background: Vitamin tests are increasingly ordered by GPs, but a clinical and evidence-based indication is often lacking. Harnessing technology (that is, decision support tools and redesigning request forms) have been shown to reduce vitamin requests ...
Saskia van Vugt, Evelien de Schepper, Sanne van Delft, Nicolaas Zuithoff, Niek de Wit, Patrick Bindels   +5 more
doaj   +1 more source

Reducing Malaria Misdiagnosis: The Importance of Correctly Interpreting Paracheck Pf® "Faint Test Bands" in a Low Transmission Area of Tanzania. [PDF]

, 2011
Although malaria rapid diagnostic tests (RDTs) have been extensively evaluated since their introduction in the early 1990's, sensitivity and specificity vary widely limiting successful integration into clinical practice.
Hatfield, Jennifer M ., Jeremy C Ho, Allen Lisa K, Ho, Jeremy C., Hatfield, Jennifer M, Manyama, Mange, Manyama Mange, Giselle DeVetten, Allen, Lisa K, Lisa K Allen, Mange Manyama, DeVetten, Giselle, Allen, Lisa K., Ho Jeremy C, Ho, Jeremy C, Jennifer M Hatfield, Hatfield Jennifer M, DeVetten Giselle   +17 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source