Results 81 to 90 of about 1,288,068 (341)

Nonparametric Predictive Inference for Ordinal Data and Accuracy of Diagnostic Tests [PDF]

, 2012
This thesis considers Nonparametric Predictive Inference (NPI) for ordinal data and accuracy of diagnostic tests. We introduce NPI for ordinal data, which are categor- ical data with an ordering of the categories.
ALI, FAIZA,FARAG
core  

Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity. [PDF]

, 2009
BACKGROUND: Sero-epidemiological methods are being developed as a tool for rapid assessment of malaria transmission intensity. Simple blood collection methods for use in field settings will make this more feasible. This paper describes validation of such
Riley, Eleanor M, Drakeley, Chris J, Clement Mweya, Cook Jackie, Eleanor M Riley, Drakeley Chris J, Stewart Laveta, Geoffrey S Williams, Mweya Clement, Williams, Geoffrey S, Cook, Jackie, Corran, Patrick H, Corran Patrick H, George Mtove, Williams Geoffrey S, Jackie Cook, Hugh Reyburn, Reyburn Hugh, Patrick H Corran, Reyburn, Hugh, Laveta Stewart, Mtove George, Stewart, Laveta, Riley Eleanor M, Mweya, Clement, Mtove, George, Chris J Drakeley   +26 more
core   +1 more source

Routine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgery: updated systematic review and meta-analysis

British Journal of Anaesthesia, 2017
Viscoelastic point-of-care tests are commonly used to provide prompt diagnosis of coagulopathy and allow targeted treatments in bleeding patients. We updated existing meta-analyses that have evaluated the clinical effectiveness of viscoelastic point-of ...
G. Serraino, G. Murphy
semanticscholar   +1 more source

Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies [PDF]

Genome Medicine, 2019
Diagnosis of primary immunodeficiencies (PIDs) is complex and cumbersome yet important for the clinical management of the disease. Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test.In May 2013, we implemented exome sequencing in routine diagnostics for patients suffering from PIDs.
Arts P, Simons A, AlZahrani MS, Yilmaz E, AlIdrissi E, van Aerde KJ, Alenezi N, AlGhamdi HA, AlJubab HA, Al-Hussaini AA, AlManjomi F, Alsaad AB, Al Saleem B, Andijani AA, Asery A, Ballourah W, Bleeker-Rovers CP, van Deuren M, van der Flier M, Gerkes EH, Gilissen C, Habazi MK, Hehir-Kwa JY, Henriet SS, Hoppenreijs EP, Hortillosa S, Kerkhofs CH, Keski-Filppula R, Lelieveld SH, Lone K, MacKenzie MA, Mensenkamp A, Moilanen J, Nelen M, ten Oever J, Potjewijd J, van Paassen P, Schuurs-Hoeijmakers JHM, Simon A, Stokowy T, van de Vorst M, Vreeburg M, Wagner A, van Well GTJ, Zafeiropoulou D, Zonneveld-Huijssoon E, Veltman JA, van Zelst-Stams WAG, Faqeih EA, van de Veerdonk FL, Netea MG, Hoischen A   +51 more
openaire   +7 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Overnight Dexamethasone Suppression Test in the Diagnosis of Cushing's Disease

Acta Medica Iranica, 2010
Realizing the cause of Cushing's Syndrome (CS) is one of the most challenging processes in clinical endocrinology. The long high dose dexamethasone suppression test (standard test) is costly and need an extended inpatient stay.
Fatemeh Esfahanian, Rozana Kazemi
doaj  

Basophil Activation Test Using Recombinant Allergens: Highly Specific Diagnostic Method Complementing Routine Tests in Wasp Venom Allergy

PLoS ONE, 2014
Background Skin testing can expose allergic subjects to potential systemic reactions, sensitization against unrelated proteins, and increased risk of future sting reactions. Therefore the continuous improvement of in vitro diagnostic methods is desirable.
L. Balzer, D. Pennino, S. Blank, H. Seismann, U. Darsow, M. Schnedler, M. McIntyre, M. Ollert, S. Durham, E. Spillner, J. Ring, L. Cifuentes   +11 more
semanticscholar   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Diagnosing brain tumours by routine blood tests using machine learning

Scientific Reports, 2019
Routine blood test results are assumed to contain much more information than is usually recognised even by the most experienced clinicians. Using routine blood tests from 15,176 neurological patients we built a machine learning predictive model for the ...
S. Podnar, M. Kukar, G. Guncar, Mateja Notar, Nina Gošnjak, Marko Notar   +5 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source