Results 121 to 130 of about 2,023,088 (340)

Some results from Monroe's diagnostic tests in arithmetic. [PDF]

, 1920
J. Wertheimer
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Diagnostic Value of the Butyric Acid Test (Noguchi) in Cerbrospinal Fluid [PDF]

, 1911
NULL AUTHOR_ID
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Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Integrating Learning from Examples into the Search for Diagnostic Policies

, 2011
This paper studies the problem of learning diagnostic policies from training examples. A diagnostic policy is a complete description of the decision-making actions of a diagnostician (i.e., tests followed by a diagnostic decision) for all possible ...
Bayer-Zubek, V., Dietterich, T. G.
core   +1 more source

Znaczenie diagnostyki i leczenia trombolitycznego w udarze nieokrwiennym mózgu = The importance of diagnosis and treatment thrombolytic in ischemic stroke

Journal of Education, Health and Sport, 2016
Siminska Joanna, Pietkun Katarzyna, Siedlecki Zygmunt, Grzyb Sebastian, Nowacka Krystyna, Hagner Wojciech, Grobelska Kinga, Beuth Wojciech. Znaczenie diagnostyki i leczenia trombolitycznego w udarze nieokrwiennym mózgu = The importance of diagnosis and ...
Joanna Siminska, Katarzyna Pietkun, Zygmunt Siedlecki, Sebastian Grzyb, Krystyna Nowacka, Wojciech Hagner, Kinga Grobelska, Wojciech Beuth   +7 more
doaj  

Individual Diagnostic Studies II. Section-picture Test [PDF]

, 1922
Schultze, Friederieke E L Otto
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Dissecting the Wjj Anomaly: Diagnostic Tests of a Leptophobic Z'

, 2011
We examine the scenario where a leptophobic Z' boson accounts for the excess of events in the Wjj channel as observed by CDF. We assume generation independent couplings for the Z' and obtain allowed regions for the four hadronic couplings using the cross
/SLAC, Hewett, J.L., Rizzo, T.G.
core   +1 more source