Results 141 to 150 of about 2,037,509 (328)

Kairos in diagnostics

Theoretical Medicine and Bioethics
AbstractKairos has been a key concept in medicine for millennia and is frequently understood as “the right time” in relation to treatment. In this study we scrutinize kairos in the context of diagnostics. This has become highly topical as technological developments have caused diagnostics to be performed ever earlier in the disease development ...
Bjørn Hofmann, Urban Wiesing
openaire   +4 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States

International Journal for Parasitology: Drugs and Drug Resistance
Ancylostoma caninum is the most significant intestinal nematode parasite of dogs. We acquired fecal surveillance data from a large population of dogs in the United States (US). A diagnostic test using real-time PCR (qPCR) for Ancylostoma spp.
Pablo D. Jimenez Castro, Jennifer L. Willcox, Haresh Rochani, Holly L. Richmond, Heather E. Martinez, Cecilia E. Lozoya, Christian Savard, Christian M. Leutenegger   +7 more
doaj   +1 more source

The Diagnostic Value of Arteriography of the Iliac Artery in Gynaecology and Obstetrics [PDF]

, 1952
Ulf Borell, I. Fernström, K. Lindblom, A. Westman   +3 more
openalex   +1 more source

A Bayesian look at diagnostics in the univariate linear model. [PDF]

This paper develops diagnostics for data thought to be generated in accordance with the general univariate linear model. A first set of diagnostics is developed by considering posterior probabilities of models that dictate which of k observations form a ...
Guttman, Irwin, Peña, Daniel
core  

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

THE DIAGNOSTIC VALUE·OF DETERMINATIONS OF PEPSIN IN GASTRIC JUICE [PDF]

, 1930
W. Scott Polland, Arthur L. Bloomfield
openalex   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

ANESTHESIA FOR CHILDREN UNDERGOING DIAGNOSTIC CARDIAC CATHETERIZATION [PDF]

, 1955
E Jay Fieldman, John S. Lundy, James W. DuShane, Earl H. Wood   +3 more
openalex   +1 more source