Results 141 to 150 of about 1,233,861 (297)

Molecular Diagnostics [PDF]

BioMed Research International, 2013
Akanchha Kesari, Ashwin Dalal, Girdhari Lal, Sachchida Nand Pandey   +3 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Correction: Al Namat et al. Omphalocele and Associated Anomalies: Exploring Pulmonary Development and Genetic Correlations-A Literature Review. <i>Diagnostics</i> 2025, <i>15</i>, 675. [PDF]

Diagnostics (Basel)
Al Namat D, Roșca RA, Al Namat R, Hanganu E, Ivan A, Hînganu D, Lupu A, Hînganu MV.   +7 more
europepmc   +1 more source

Diagnostic Study of a Synthetic Human Corticotropin-Releasing Hormone (hCRH) in Healthy Adult Males: Its Plasma Pharmacokinetics and the Effects on the Urinary Excretion of Steroid Hormones.

, 1993
KOSHI TANAKA, MECUMI NAGATA, Sachiko Itoh, Munehito Kumagae, N Shimizu   +4 more
openalex   +2 more sources

Role of Diagnostic Office Hysteroscopy in Abnormal Uterine Bleeding and its Histopathological Correlation in Child Bearing Period [PDF]

, 2020
Maluk Mohamed, Manal Abdel Fattah, S.N. Abo El Ezz, Doaa Mahmoud Akasha Mohamed   +3 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Diagnostic accuracy of ultrasound in common acute abdominal conditions

, 2019
Shashank C. Deshmukh, A. Manmadha Kishan
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Special Issue "Advances in Diagnostics: Applications of Nucleic Acids and Their Analogs". [PDF]

Int J Mol Sci
Masi A, Pascucci B, Moccia M.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source