Results 161 to 170 of about 1,002,484 (308)

O62: Frequency and implications of likely maternal segmental aneusomies identified on cell-free DNA prenatal screening

Genetics in Medicine Open
Sarah South, Dina Ahram, Ben Anderson, Lisa Blazejewski, Guity Ghaffari, Mingjuan Liao, Kayla Livingston, Tessa Niemchak, Carole Oddoux, Franklin Quan, Jennifer Rion, Meenakshi Sharma, Timothy Vo, Guoli Wang, Yili Xie, Hui Yang   +15 more
doaj   +1 more source

Older Patients With Memory Complaints Often Prefer Diagnostics in Primary Care or No Further Diagnostic Evaluation. [PDF]

Int J Geriatr Psychiatry
Ronner D, Richard E, van Charante EPM, van Gool WA, Schers HJ, Perry M.   +5 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Comment on Chen et al. Vestibulo-Ocular Reflex Results in Patients with Intralabyrinthine Schwannomas: Case Series with a Literature Review. <i>Diagnostics</i> 2025, <i>15</i>, 2093. [PDF]

Diagnostics (Basel)
Ionescu EC.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

P223: Multiplex detection and quantification of neurological disease-associated repeat expansions using the PacBio Sequel IIe platform

Genetics in Medicine Open
Fabio Fuligni, Robert Thaenert, Aidan Hennigan, Duncan Kilburn, Valeriya Gaysinskaya, Egor Dolzhenko, Guilherme De Sena Brandine, Sarah Kingan, Jason Evans, Danuta Hietpas, Hannah White, Tamara Smith, Timothy Looney, Ray Veeraraghavan, Tina Hambuch-Hawks, Christopher Elzinga, Meaghan Russell   +16 more
doaj   +1 more source

Awareness and adoption intent of cutaneous interstitial fluid-based biomarkers in autoimmune dermatoses among healthcare students: A descriptive cross-sectional study. [PDF]

Medicine (Baltimore)
Kandasamy G, Orayj K, Asiri R, Alshahrani AM, Alzaydani A, Vasudevan R, Osman HA, Elfadil H, Sharif Y, Abu-Elfotuh K, Mani V, Prabahar K.   +11 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Towards a framework for prioritizing diagnostics in the global AMR response. [PDF]

JAC Antimicrob Resist
Bansal A.
europepmc   +1 more source