Results 171 to 180 of about 1,002,484 (308)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Toward an Affordable Density-Based Measure for the Quality of a Coupled Cluster Calculation. [PDF]

J Phys Chem A
Jones GH, Weflen KE, Martin JML.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Formal compliance versus functional access to diagnostics in the PhilHealth primary care benefit package: a glimpse into a rural health unit in the Philippines. [PDF]

Trop Med Health
Kanamori S, Bonhaon MD, Egami Y, Evangelista NM, Marayag NG, Villanueva AFDR, Uechi M, Ramones RAJ, Umalco ML, Fujita M.   +9 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Correction: Edris et al. Temporal Bone Fractures on High-Resolution CT: Bridging Radiologic Detail with Otologic Anatomy and Surgical Implications. <i>Diagnostics</i> 2026, <i>16</i>, 718. [PDF]

Diagnostics (Basel)
Edris OMK, Adam AB, Albadawi EA, ALGhabban AM, Alqarni RSM, Owaydhah WH, Alharthi OA, Khattab E, Alharbi F, Elhassan YH.   +9 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Advancing diagnostics for Chagas disease: key product characteristics and harmonized evaluation strategies - an expert meeting report. [PDF]

BMC Infect Dis
Bohorquez LC, Schijman AG, Perez F, Coto H, Marchiol A, Pinazo MJ.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Infectious disease diagnostic competencies of medical students as a fundamental basis for physicians' resilience in addressing future infectious disease challenges. [PDF]

GMS Infect Dis
Brandt C, Becker K, Ciesek S, Dittmer U, Kempf VAJ, Löffler B, Mattner F, Pfeffer K, Jantsch J.   +8 more
europepmc   +1 more source