FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Correction: Bednarek et al. Serum Osteoprotegerin Level Is Not a Localizing Biomarker of Atherosclerosis Affected by Kidney Function. <i>Diagnostics</i> 2026, <i>16</i>, 786. [PDF]
Diagnostics (Basel)Bednarek AM +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Precision cancer medicine in Europe: a mixed-methods study on infrastructure for extended molecular diagnostics. [PDF]
J Cancer Res Clin OncolHenkel PS +8 more
europepmc +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Reply to Rugge, M. Autoimmune Gastritis Diagnosis: Encompassing Pessimism, Realism, and Wish for the Future. Comment on "Vienneau et al. Autoimmune Metaplastic Atrophic Gastritis Reporting: Are Pathologists and Endoscopists on the Same Page? <i>Diagnostics</i> 2025, <i>15</i>, 2906". [PDF]
Diagnostics (Basel)Vienneau N, Lee H, Tadros M.
europepmc +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Autoimmune Gastritis Diagnosis: Encompassing Pessimism, Realism, and Wish for the Future. Comment on Vienneau et al. Autoimmune Metaplastic Atrophic Gastritis Reporting: Are Pathologists and Endoscopists on the Same Page? <i>Diagnostics</i> 2025, <i>15</i>, 2906. [PDF]
Diagnostics (Basel)Rugge M.
europepmc +1 more source
P271: Beyond SMN1: Review of genotype-phenotype correlation in individuals with ≥4 SMN2 copy numbers
Genetics in Medicine Open, 2023 Zoe Powis +3 more
doaj +1 more source