Results 21 to 30 of about 9,615 (225)

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

DIRGLIŲ GERKLŲ SINDROMAS: ŠIUOLAIKINĖ DIAGNOSTIKA IR GYDYMAS

, 2017
Straipsnyje detaliai nagrinėjama suaugusių asmenų dirglių gerklų sindromo terminai, patogenezė ir priežastys, aprašoma dirglių gerklų sindromo diagnostika atsižvelgiant į anamnezę, simptomus ir laringoskopijos požymius.
Sigutė Norkienė, Asta Aukštakalnienė, Nora Šiupšinskienė   +2 more
core   +1 more source

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study

Aging Cell, Volume 25, Issue 6, June 2026.
Can we boost vaccine responses in older adults? In a double‐blind, randomised, placebo‐controlled pilot study (n = 40, > 65 years), spermidine supplementation (6 mg/day, 13 weeks) was safe and significantly improved immune responses following a 3rd SARS‐CoV‐2 vaccine dose.
Ghada Alsaleh, Mohammad Ali, Amir Hossein Kayvanjoo, Feng Liu, Tanaïs Moreau, Sagida Bibi, Lin Luo, Melissa Govender, Miles Carroll, Sebastian J. Hofer, Eisenberg Tobias, Christoph Magnes, Loren Kell, Christopher Chung, Yu Deng, Aneesha Bhandari, Lucy Garner, Thomas Conrad, Liye Chen, Barbara Kronsteiner‐Dobramysl, Susie Dunachie, Owen B. Spiller, Teresa Lambe, Paul Klenerman, Lucy C. Jones, A. Katharina Simon   +25 more
wiley   +1 more source

Antenataalse diagnostika tähtsusest gastroskiisiga laste ravis

, 2003
Gastroskiis on kaasasündinud väärarend, mille puhul kõhu eeseinal asetseva defekti kaudu on eventreerunud kõhukoopa elundid. Aastatel 1991–2001 sündis Eestis 39 gastroskiisiga last.
Varik, Karin, Kirsimägi, Ülle, Reino, Udo, Ehrenberg, Aivar, Varik, Indrek   +4 more
core   +1 more source

Hyperaldosteronism in Mice Lacking the Distal Polybasic Tract of the γ‐Subunit of the Epithelial Sodium Channel During Sodium Restriction

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aims The epithelial sodium channel ENaC consists of the subunits α, β, and γ and is activated at an individual channel level by proteolytic processing. Murine γENaC contains a distal polybasic tract 186RKRK mediating proteolytic ENaC activation by serine proteases in vitro.
Daniel Essigke, M. Zaher Kalo, Matthias Wörn, Xia‐Qing Li, Bernhard N. Bohnert, Anja Schork, Andreas L. Birkenfeld, Thomas Ott, Ferruh Artunc   +8 more
wiley   +1 more source

Physiological adaptation during heart rate variability biofeedback in young adults: A survival analysis in high‐stress academic environments

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Medical education is a high‐demand environment where stress may disrupt autonomic and HPA‐axis regulation. We examined symptom trajectories and adaptation during heart rate variability biofeedback (HRV‐BF) in an academic setting. Forty‐seven students were followed for ~3 months.
Gabriela Panayotova, Margarita Velikova
wiley   +1 more source

Ausgewählte unionsrechtliche Rechtsfragen zu Medizinprodukten und In-vitro-Diagnostika

, 2022
Mit dem Erlass der MDR und IVDR hat die EU für ihre Mitgliedstaaten einen einheitlichen Rechtsrahmen im Bereich der Medizinprodukte und In-vitro-Diagnostika geschaffen.
Wilhelm, Iris
core  

Priporočila za obravnavo bolnikov z rakom glave in vratu v Sloveniji

Onkologija, 2021
Priporočila za obravnavo rakov glave in vratu (RGV) v Sloveniji sledijo priporočilom in usmeritvam, povzetim v publikaciji neprofitne mreže 30 vodilnih severnoameriških inštitucij za obravnavo raka, National Comprehensive Cancer Network, in hkrati ...
Primož Strojan, Aleksandar Aničin, Jelena Azarija, Saba Battelino, Bogdan Čizmarevič, Vojko Didanović, Tadej Dovšak, Marta Dremelj, Aleš Fidler, Matic Glavan, Cvetka Grašič-Kuhar, Aleš Grošelj, Andrej Kansky, Katarina Karner, Marko Kokalj, Matic Koren, Jana Krapež, Hojka Kuralt, Boštjan Lanišnik, Primož Levart, Jure Orel, Jošt Pavčič, Gaber Plavc, Luka Prodnik, Peter Pukl, Robert Šifrer, Matija Švagan, Jure Urbančič, Branko Zakotnik, Nina Zidar, Barbara Žumer   +30 more
doaj  

Tumor‐Immune‐On‐Chip to Evaluate Pathophysiological Feature of T Lymphocytes Expanded from Patient Tumors and Lymph Node Tissues

Cancer Medicine, Volume 15, Issue 5, May 2026.
3D Tumor‐Immune On‐Chip reveals patient‐derived tumor‐infiltrating lymphocytes (TILs) exhibit superior infiltration and cytotoxicity against colorectal cancer spheroids compared to lymph node T cells, providing a platform to study patient‐specific tumor‐immune interactions for developing personalized cancer immunotherapies.
Gyu‐Bon Cho, Hyun‐Joo Lee, You Jeong Heo, Jihoon Ko, Won‐Suk Lee, Sujin Hyung   +5 more
wiley   +1 more source

Įmonių diagnostika - jų valdymo dedamoji

, 2007
This paper deals with the key factors of enterprise diagnostics and describes research findings by abstract models. Enterprise diagnostics deals with the recognition and evaluation of all aspects of company processes and with the therapy devices ...
Ďurišová, Mária
core   +1 more source