Results 41 to 50 of about 2,325,912 (296)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
On the Triple Square and the Diagonal of the Golden Section [PDF]
Nexus Network Journal, 2002 Geometer Mark Reynolds demonstrates the use of an ancient system for new ways of thinking and seeing: on the triple square and the diagonal of the Golden Section.
openaire +1 more source
Journal of High Energy Physics, 2019 In this note we describe a method to calculate the action of a particular Fourier-Mukai transformation on a basis of brane charges on elliptically fibered Calabi-Yau threefolds with and without a section.
Thorsten Schimannek
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
“Fabriquer l’hospitalité tout contre la ville hostile”
, 2023 Au cours de l’atelier “Reconsidérer l’urbanisme en toute hospitalité”, organisé dans le cadre de la 26e Université d’été du CFDU à Grenoble, l’architecte Sébastien Thiéry a présenté l’activité engagée et innovante du Pôle d’exploration des ressources ...
Revue d'urbanisme Diagonal
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Non-diagonal critical central sections of the cube [PDF]
Advances in MathematicsWe study the $(n-1)$-dimensional volume of central hyperplane sections of the $n$-dimensional cube $Q_n$. Our main goal is two-fold: first, we provide an alternative, simpler argument for proving that the volume of the section perpendicular to the main diagonal of the cube is strictly locally maximal for every $n \geq 4$, which was shown before by L ...
Ambrus Gergely, Gárgyán Barnabás
openaire +3 more sources
La parole à Sébastien Thiéry, coordinateur des actions du PEROU
, 2022 Au cours de l’atelier "Reconsidérer l’urbanisme en toute hospitalité", organisé dans le cadre de la 26ème Université d'été du CFDU à Grenoble (lire l'article consacré), l’architecte Sébastien Thiéry a présenté l’activité engagée et innovante du Pôle d ...
Revue d'urbanisme Diagonal
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