Results 231 to 240 of about 7,646 (295)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

The 60:40 conundrum: are women with CKD discriminated after referral to a nephrology clinic? [PDF]

Clin Kidney J
Vautcranne A, Bianco L, Mazé B, Fois A, Chatrenet A, Moio MR, Santagati G, Njandjo L, de Müllenheim PY, Torreggiani M, Piccoli GB.   +10 more
europepmc   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Kidney health during critical illness or upon major surgery. [PDF]

Nephrol Dial Transplant
Saritas T, Cantaluppi V, Sanz AB, Faguer S, Gameiro J, Lopes JA, de Seigneux S, Ostermann M, Selby NM.   +8 more
europepmc   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

[Recommendations for the Diagnosis and Treatment of Chronic Kidney Disease (CKD) by the Austrian Society of Nephrology]. [PDF]

Wien Klin Wochenschr
Ksiazek SH, Windpessl M, Zitt E, Rudnicki M, Eller K, Schwarz C, Antlanger M, Schmaldienst S, Cejka D, Oberbauer R, Rosenkranz AR, Säemann MD.   +11 more
europepmc   +1 more source

Nanowires Reinforce Oriented Macroporous Aerogels for Rapid Uranium Removal from Acidic Radioactive Wastewater

Advanced Science, EarlyView.
A “reinforced concrete” structural aerogel with directional microchannels is engineered for rapid uranium capture. The interconnected architecture enables ultrafast water permeation, and the nanowire reinforcement yields a 70‐fold increase in mechanical strength.
Ze Liu, Simin Guan, Se Shi, Hao Wang, Wenya Zhou, Hui Wang, Tao Liu, Yihui Yuan, Ning Wang   +8 more
wiley   +1 more source

Recurrence of preeclampsia is common, even during rigorously controlled multidisciplinary follow-up: a pilot experience. [PDF]

Clin Kidney J
De Marco O, Ruotolo C, Njanjo L, Mariani C, Mazé B, Santagati G, Fois A, Chevé MT, Chatrenet A, Salomone M, Torreggiani M, Piccoli GB.   +11 more
europepmc   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

The 129S1/SvlmJ mouse strain recapitulates severe hypertensive target organ damage under moderate angiotensin II-induced hypertension. [PDF]

Sci Rep
Orieux A, Boulestreau R, Bats ML, Michot M, Boyer A, Dinet V, Vaurs J, Dufourcq P, Peghaire C, Duplaa C, Couffinhal T, Rubin S.   +11 more
europepmc   +1 more source