Results 61 to 70 of about 934,602 (387)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

A clinical nomogram for the prediction of early mortality in elderly patients initiating dialysis for end-stage renal disease

Renal Replacement Therapy, 2020
Background The number of elderly patients (> 80 years of age) with end-stage renal disease is rapidly increasing. The initiation of dialysis extends the duration of survival; however, the rate of early mortality, that which occurs within the first few ...
Masaki Yoshida, Masanori Otsuka, Yoshikazu Watanabe, Takako Harigai, Noriyuki Sakurai, Keiko Kobatake, Hiroaki Yoshida, Satsuki Kobayashi, Takayuki Matsumoto, Tatsuhiko Sakamoto, Kazue Ueki   +10 more
doaj   +1 more source

Committee report: Questionnaire survey on the treatment of COVID-19 in patients receiving dialysis therapy

Renal Replacement Therapy, 2022
Background Patients with coronavirus disease 2019 (COVID-19) who receive dialysis therapy develop more severe disease and have a poorer prognosis than patients who do not.
Ayumi Yoshifuji, Munekazu Ryuzaki, Yuki Uehara, Norio Ohmagari, Toru Kawai, Yoshihiko Kanno, Kan Kikuchi, Hiroshi Kon, Ken Sakai, Toshio Shinoda, Yaoko Takano, Junko Tanaka, Kazuhiko Hora, Yasushi Nakazawa, Naoki Hasegawa, Norio Hanafusa, Fumihiko Hinoshita, Keita Morikane, Shu Wakino, Hidetomo Nakamoto, Yoshiaki Takemoto   +20 more
doaj   +1 more source

Irinotecan Hydrochloride (CPT-11) in Dialysis Patients with Gastrointestinal Cancer [PDF]

, 2010
We investigated changes in drug disposition and toxicities with CPT-11 in 15 dialysis patients with gastrointestinal cancers to clarify whether CPT-11 could be administered safely in such patients.
Akashi, Isao, Ashizawa, Tatsuto, Hama, Kouichirou, Hirano, Toshihiko, Iwahori, Tohru, Iwamoto, Hitoshi, Jyojima, Yoshimaro, Kihara, Yuu, Konnno, Osamu, Nagao, Takeshi, Nakamura, Yuuki, Segawa, Mai, Takeuchi, Hironori, Yokoyama, Takayoshi   +13 more
core   +1 more source

Brazilian chronic dialysis survey 2017

Jornal Brasileiro De Nefrologia, 2019
Introduction: Having national data on chronic dialysis is essential in treatment planning. Objective: To present data of the survey from the Brazilian Society of Nephrology on patients with chronic kidney disease on dialysis in July 2017.
F. Thomé, R. Sesso, A. Lopes, J. Lugon, C. Martins   +4 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Comparison of peritoneal dialysis and hemodialysis as first renal replacement therapy in patients with end-stage renal disease and diabetes: a systematic review

Renal Replacement Therapy, 2019
Background Diabetes has become the most common cause of end-stage renal disease (ESRD) requiring renal replacement therapy (RRT) in most countries around the world.
Yukio Maruyama, Chieko Higuchi, Hiroaki Io, Keiichi Wakabayashi, Hiraku Tsujimoto, Yasushi Tsujimoto, Hidemichi Yuasa, Munekazu Ryuzaki, Yasuhiko Ito, Hidetomo Nakamoto   +9 more
doaj   +1 more source

Narrative Review of Incremental Hemodialysis. [PDF]

, 2020
The prescription of hemodialysis (HD) in patients with incident end-stage kidney disease (ESKD) is fundamentally empirical. The abrupt transition from nondialysis chronic kidney disease (CKD) to thrice-weekly in-center HD of much the same dialysis ...
Garneata, Liliana, Kalantar-Zadeh, Kamyar, Moossavi, Shahriar, Murea, Mariana   +3 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Evaluation of frailty status and prognosis in patients aged over 75 years with chronic kidney disease (CKD)

Renal Replacement Therapy, 2020
Background There is a higher frequency of advanced chronic kidney disease (CKD) in frail patients than in the general population. This study evaluated frailty status before initiation of dialysis and clarified the prognosis in patients aged over 75 years
Masaki Yoshida, Yurie Takanashi, Takako Harigai, Noriyuki Sakurai, Keiko Kobatake, Hiroaki Yoshida, Satsuki Kobayashi, Takayuki Matsumoto, Kazue Ueki   +8 more
doaj   +1 more source