Results 131 to 140 of about 11,048,365 (245)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Dialysis-related data of peritoneal dialysis patients with or without oral tori (n = 134).

open access: yes, 2016
Dialysis-related data of peritoneal dialysis patients with or without oral tori (n = 134).
Cheng-Hao Weng (166471)   +12 more
core   +1 more source

Therapeutic potential of amino acid-based peritoneal dialysis solutions: a systematic review

open access: yesBMC Nephrology
Peritoneal dialysis (PD) offers many advantages over hemodialysis but chronic exposure to bio-incompatible glucose-based PD solutions and continuous absorption of glucose from the dialysate may lead to peritoneal membrane (PM) dysfunction and systemic ...
Bengt Lindholm   +13 more
doaj   +1 more source

Current Progress in Peritoneal Dialysis: A Narrative Review of Progress in Peritoneal Dialysis Fluid

open access: yesLife
Peritoneal dialysis (PD) is a renal replacement therapy that removes solutes, electrolytes, and water via the infusion of dialysis fluid into the peritoneal cavity. However, the non-physiological composition of conventional PD fluids can cause peritoneal
Koji Hashimoto, Yuji Kamijo
doaj   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

open access: yesAdvanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris   +11 more
wiley   +1 more source

Feeding during dialysis—risks and uncertainties

open access: yes, 2017
Allowing dialysis patients to eat during the treatment is controversial. It is, therefore, no surprise that practices and policies with respect to intradialytic food consumption vary considerably from unit to unit and from country to country.
Panagiotis Georgianos   +3 more
core   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

open access: yesAdvanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang   +12 more
wiley   +1 more source

UCST‐Responsive PMEGA: From Solution Behavior to Functional Hydrogel Surfaces

open access: yesAdvanced Materials Interfaces, EarlyView.
PMEGA is used as a versatile water‐based UCST‐responsive platform for engineering microstructured hydrogel coatings via a thiol–ene CLAG approach. From PMEGAs of well‐defined UCST properties, the UV‐based CLAG method provides precise control over film thickness, ranging from nanometers to micrometers, and enables high‐resolution patterning.
Thi Phuong Thu Nguyen   +4 more
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Adequacy of dialysis in automated peritoneal dialysis: A clinical experience

open access: yes, 1997
Objectives: To compare the peritoneal clearances of urea and creatinine in continuous ambulatory peritoneal dialysis (CAPD) with three types of automated peritoneal dialysis (APD): continuous cycling peritoneal dialysis (CCPD), 50% tidal peritoneal ...
Vega Díaz, Nicanor   +7 more
core  

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