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Supplemented Dialysis: Amino Acid-Based Solutions in Peritoneal Dialysis
2015Peritoneal dialysis is associated with several metabolic and nutritional abnormalities, some of which are related to the use of glucose-based solutions. Furthermore, the catabolic effects of uremia per se, protein and amino acid losses into the dialysate, peritonitis and poor appetite contribute to amino acid abnormalities, negative nitrogen balance ...
B, Lindholm, M S, Park, J, Bergström
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Choice of Peritoneal Dialysis Solutions
Annals of Internal Medicine, 1971Excerpt Peritoneal dialysis enjoys increasing popularity in the treatment of both acute and chronic renal failure despite its complications.
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Peritoneal damage by peritoneal dialysis solutions
Clinical and Experimental Nephrology, 2008Continuous ambulatory peritoneal dialysis is a well-accepted treatment for end-stage renal disease, but its long-term success is limited. Peritoneal sclerosis is still one of the most important complications of long-term peritoneal dialysis and the low biocompatibility of peritoneal dialysis solutions plays a major role in the development of such ...
Takafumi, Ito, Noriaki, Yorioka
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2011
>PD has traditionally been performed with acidic solutions containing glucose as osmotic and lactate as buffer agent. These solutions confer marked local and systemic toxicity (Fig. 12.1). Within few years, the peritoneal membrane undergoes profound morphological transformations including progressive mesothelial denudation, submesothelial fibrosis ...
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>PD has traditionally been performed with acidic solutions containing glucose as osmotic and lactate as buffer agent. These solutions confer marked local and systemic toxicity (Fig. 12.1). Within few years, the peritoneal membrane undergoes profound morphological transformations including progressive mesothelial denudation, submesothelial fibrosis ...
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Peritoneal Dialysis Solution and Nutrition
201220-70% of peritoneal dialysis patients have some signs of malnutrition. Anorexia, protein and amino acid losses in dialysate, advanced age of elderly patients, inflammation and cardiac failure are among the main causes. Modern dialysis solutions aim to reduce these causes, but none of them is without side effects: glucose is relatively safe and brings ...
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Glucotoxicity in Peritoneal Dialysis—Solutions for the Solution!
Advances in Chronic Kidney Disease, 2007Glucose has served well as the prototypical osmotic agent in peritoneal dialysis for more than 2 decades, because it affords many of the characteristics required of a safe and effective osmotic agent. The disadvantages of glucose include its rapid dissipation from the peritoneum and its resulting limited UF efficiency capacity in high and high-average ...
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Dialysis Solutions and Equipment
1993Dialysis solutions for CAPD are available in different glucose concentrations (0.5, 1.5, 2.5, and 4.25 g% of monohydrate glucose) and volumes (0.25, 0.5, 0.75, 1.0, 2.0, 2.5, and 3 liters) packaged in clear under-filled plastic bags of potential volume almost 50% more than the solution volume.
Ramesh Khanna +2 more
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New peritoneal dialysis solutions
Nephrology, 1996Summary: Current peritoneal dialysis solutions are not biocompatible, particularly in respect to low pH, high osmolality and use of lactate. In addition, glucose is not an ideal osmotic agent. Recent advances in the formulation of peritoneal dialysis fluids aim to provide a more physiological environment to preserve membrane integrity.
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[Alternative dialysis solutions in continuous ambulatory peritoneal dialysis].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999Not satisfactory enough long-term results of applying glucose in CAPD solutions as an osmotic agent were the reason of research on the alternative osmotic substances. The paper presents review of actually used solutions containing amino acids (Nutrineal) or polymer glucose (Icodextrin).
A, Olszowska, D, Baczyński
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