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Newer Peritoneal Dialysis Solutions

Advances in Renal Replacement Therapy, 2000
Currently available peritoneal dialysis (PD) solutions provide for adequate removal of metabolic waste and manage fluid and electrolyte imbalances. They are, however, bioincompatible and do lead to peritoneal membrane changes with long-term use. Glucose is now strongly implicated in this.
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Peritoneal Dialysis Solution and Nutrition

2012
20-70% of peritoneal dialysis patients have some signs of malnutrition. Anorexia, protein and amino acid losses in dialysate, advanced age of elderly patients, inflammation and cardiac failure are among the main causes. Modern dialysis solutions aim to reduce these causes, but none of them is without side effects: glucose is relatively safe and brings ...
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Peritoneal Dialysis Solutions

2021
The peritoneal dialysis solution (PDS) is the cornerstone of peritoneal dialysis (PD), responsible for both fluid removal and metabolic control. The absolute requirements for a PDS are a buffer to manage acidosis, an osmotic agent to produce ultrafiltration, and electrolytes including sodium, chloride, calcium, and magnesium to maintain homeostasis ...
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Peritoneal damage by peritoneal dialysis solutions

Clinical and Experimental Nephrology, 2008
Continuous ambulatory peritoneal dialysis is a well-accepted treatment for end-stage renal disease, but its long-term success is limited. Peritoneal sclerosis is still one of the most important complications of long-term peritoneal dialysis and the low biocompatibility of peritoneal dialysis solutions plays a major role in the development of such ...
Takafumi, Ito, Noriaki, Yorioka
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Peritoneal Dialysis Solutions for the 21st Century

Artificial Organs, 1998
Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradation products.
L, Martis, C, Chen, J B, Moberly
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Optimum Electrolyte Composition of a Dialysis Solution

Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2008
In patients undergoing peritoneal dialysis (PD) for end-stage renal failure, the optimum electrolyte composition of a dialysis solution is that which best serves the homeostatic needs of the body. Comparing the trans-peritoneal removal of electrolytes by conventional PD solutions (CPDSs) with that by normal kidneys, it is evident ...
Bengt, Rippe, Daniele, Venturoli
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Dialysis Solutions and Equipment

1993
Dialysis solutions for CAPD are available in different glucose concentrations (0.5, 1.5, 2.5, and 4.25 g% of monohydrate glucose) and volumes (0.25, 0.5, 0.75, 1.0, 2.0, 2.5, and 3 liters) packaged in clear under-filled plastic bags of potential volume almost 50% more than the solution volume.
Ramesh Khanna   +2 more
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Supplemented Dialysis: Amino Acid-Based Solutions in Peritoneal Dialysis

2015
Peritoneal dialysis is associated with several metabolic and nutritional abnormalities, some of which are related to the use of glucose-based solutions. Furthermore, the catabolic effects of uremia per se, protein and amino acid losses into the dialysate, peritonitis and poor appetite contribute to amino acid abnormalities, negative nitrogen balance ...
B, Lindholm, M S, Park, J, Bergström
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Peritoneal Dialysis Solutions

2011
>PD has traditionally been performed with acidic solutions containing glucose as osmotic and lactate as buffer agent. These solutions confer marked local and systemic toxicity (Fig. 12.1). Within few years, the peritoneal membrane undergoes profound morphological transformations including progressive mesothelial denudation, submesothelial fibrosis ...
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