Results 51 to 60 of about 168,633 (304)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Dialysis resource allocation in critical care: the impact of the COVID-19 pandemic and the promise of big data analytics

Frontiers in Nephrology, 2023
The COVID-19 pandemic resulted in an unprecedented burden on intensive care units (ICUs). With increased demands and limited supply, critical care resources, including dialysis machines, became scarce, leading to the undertaking of value-based cost ...
Farrukh M. Koraishy, Sandeep K. Mallipattu   +1 more
doaj   +1 more source

Perturbed angular correlation study of a haptenic molecule [PDF]

, 1972
The angular correlation of the 173-247 keV gamma-ray cascade after the electron-capture decay of (111)In is strongly perturbed when the I-p-nitrophenylethylenediaminetetraacetate chelate of (111)In(3+) is added to a solution containing rabbit antibody ...
Baldeschwieler, John D., Meares, Claude F., Sundberg, Michael W.   +2 more
core  

An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core [PDF]

, 2015
Silver nanoparticles have antibacterial properties, but their use has been a cause for concern because they persist in the environment. Here, we show that lignin nanoparticles infused with silver ions and coated with a cationic polyelectrolyte layer form
A Duval, A Kumar, A Panáček, A Panáček, A Verma, AE Nel, Alexander P. Richter, AM El Badawy, Amy Wang, Bhuvnesh Bharti, C Frangville, C Ge, C Levard, C Wandrey, E Jeong, Elaine A. Cohen Hubal, G Marchant, GA Sotiriou, H Harmita, H Lara, HA Wege, I Sondi, J Dobias, J Fabrega, Joseph S. Brown, JR Morones, K Lundquist, K Poole, Keith Houck, L Petridis, M Ahamed, M Lundqvist, M Norgren, M Rai, MP Monopoli, O Choi, Orlin D. Velev, P Anastas, P Gélinas, P Raveendran, QL Feng, R Justo-Hanani, R Kavlock, S Kim, S Langsrud, S Tan, Simeon D. Stoyanov, SL Chinnapongse, ST Stern, Sumit Gangwal, T Silva, T Walser, TDH Bugg, Vesselin N. Paunov, VK Sharma, VK Sharma, X Guo, Y Matsumura, Z Xiu   +58 more
core   +2 more sources

Update on peritoneal dialysis solutions [PDF]

Kidney International, 2007
Since the widespread introduction of peritoneal dialysis (PD) into the standard care of patients with chronic kidney disease there has been a shift from the initial focus on technique survival to refinement of the therapy to enhance biocompatibility and improve both the local peritoneal and systemic consequences of PD.
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Risk of hypoglycemia during hemodialysis in diabetic patients is related to lower pre-dialysis glycemia

Archives of Endocrinology and Metabolism
Objective To compare the occurrence of hypoglycemia during hemodialysis in chronic kidney disease diabetic patients who present different levels of pre-dialysis glycemia both when using dialysis solutions with and without glucose.
Jayme Eduardo Burmeister, Diego da Rosa Miltersteiner, Bruna Ortega Burmeister, Juliana Fernandes Campos   +3 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Results of a novel screening tool measuring dietary sodium knowledge in patients with chronic kidney disease. [PDF]

, 2015
BackgroundReducing dietary sodium has potential to benefit patients with chronic kidney disease (CKD). Little research is available defining dietary sodium knowledge gaps in patients with pre-dialysis CKD.
Anderson, Cheryl AM, Cavanaugh, Kerri L, Greene, Jane H, Ikizler, Talat Alp, Wright Nunes, Julie A   +4 more
core   +1 more source