Results 101 to 110 of about 1,706,764 (337)
Materials Research Express, 2020 Localized electrochemical deposition (LECD) is a promising method for three-dimensional micro-/nanofabrication and, thus, the factors influencing LECD have been intensively investigated.
Qixin Qing, Fuliang Wang
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Discrete Applied Mathematics, 1992 AbstractWe prove that a graph with maximum degree 3 and diameter d≥4 cannot have exactly two vertices less than the Moore bound.
openaire +3 more sources
The roles and applications of extracellular vesicles in cancer
Molecular Oncology, EarlyView.Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Prediction Model of Wooden Logs Cutting Patterns and Its Efficiency in Practice
Applied Sciences, 2020 This article deals with the testing of a methodology for creating log cutting patterns. Under this methodology, programs were developed to optimize the log yield. Testing was conducted by comparing the values of the proportions of the individual products
Tomáš Gergeľ +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Large Cayley graphs of small diameter [PDF]
arXiv, 2017 The degree-diameter problem seeks to find the largest possible number of vertices in a graph having given diameter and given maximum degree. Very often the problem is studied for restricted families of graph such as vertex-transitive or Cayley graphs, with the goal being to find a family of graphs with good asymptotic properties.
arxiv
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source