Results 91 to 100 of about 28,431 (153)

The molecular mechanism of sepsis-induced diaphragm dysfunction. [PDF]

J Thorac Dis, 2023
Yuan X, Xue F, Yu Y, Cao X, Han Y, Wang F, Zhong L.   +6 more
europepmc   +1 more source

The acute effects of exercise on fetal well‐being in pregnancies complicated by fetal growth restriction with normal Dopplers: A prospective study

Pregnancy, Volume 2, Issue 5, September 2026.
Abstract Background The potential risks and benefits of moderate‐intensity exercise in the management of fetal growth restriction (FGR) are controversial. Objective We sought to evaluate fetal responses to a 30‐min bout of moderate‐intensity exercise in pregnancies complicated by FGR.
Alissa Paudel, Jill M. Maples, Linda Szymanski, Rachel Tinius, Nikki B. Zite, Kristina Carter, Gregory S. Hawk, Kimberly B. Fortner   +7 more
wiley   +1 more source

Association between diaphragm excursion and whole-body muscle mass in older adults: an observational study

Scientific Reports
Symptoms of diaphragm dysfunction, such as exertional dyspnea and decreased exercise tolerance, share similarities with the symptoms of skeletal muscle mass reduction caused by conditions like sarcopenia.
Shuji Ouchi, Toru Yamada, Takahiro Shinohara, Suguru Mabuchi, Kazuharu Nakagawa, Kanako Yoshimi, Ayane Horike, Tatsuya Mayama, Kenji Toyoshima, Yoshiaki Tamura, Atsushi Araki, Ryoichi Hanazawa, Akihiro Hirakawa, Hiroyuki Ichige, Takeshi Ishida, Takuma Kimura, Haruka Tohara, Masayoshi Hashimoto   +17 more
doaj   +1 more source

Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1821-1831, August 2026.
ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair, Kevin Carratu, Natalie E. Rintoul, Holly L. Hedrick, William H. Peranteau, Catherine M. Avitabile, Kirsty McWalter, Paul Kruszka, Ian D. Krantz, K. Taylor Wild   +9 more
wiley   +1 more source

Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Schematic diagram of the manufacturing process of exosomes‐cardiac homing peptide (Exo‐CHP) and its therapeutic effects for Duchenne muscular dystrophy (DMD) cardiomyopathy. Abstract Background Duchenne muscular dystrophy (DMD)‐associated cardiomyopathy is a leading causes of premature death, yet treatment options remain limited.
Qihong Wu, Yiyuan Xue, Kun Zhang, Ke Xu, Ting Xu, Hang Fu, Suming Zhang, Meng Zhang, Ran Sun, Sophelia Hoi Shan Chan, Linyuhan Zhou, Xiaotang Cai, Yingkun Guo, Huayan Xu   +13 more
wiley   +1 more source

Downstream Pathways of Dystrophin Deficiency in Duchenne Muscular Dystrophy: Implications for Muscle Degeneration and Regeneration

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy, primarily affecting skeletal muscle and leading to premature death. Although the loss of dystrophin has long been recognised as the primary cause of the disease, no definitive cure is currently available. As a consequence, therapeutic efforts
Raffaele Epis, Gabriele Rovetta, Giulia Ferrari, Chiara Bonfanti, Giorgia Careccia, Graziella Messina   +5 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Congenital CMV associated with diaphragm dysfunction: a rare cause of tachypnoea. [PDF]

BMJ Case Rep, 2023
Carter R, Yakir M, Ryu J, Weiss K.
europepmc   +1 more source

Neuroprotective Effects of RNS60 in TDP‐43 Pathology‐Associated Amyotrophic Lateral Sclerosis

Muscle &Nerve, Volume 74, Issue 2, Page 463-473, August 2026.
ABSTRACT Introduction TDP‐43 pathology is broadly observed in the cerebral cortex of patients with amyotrophic lateral sclerosis (ALS). RNS60, an experimental treatment for acute ischemic stroke and ALS, enhanced mitochondrial biogenesis and function in other preclinical models.
Danny R. Vesevick, Supurna Ghosh, Andreas Kalmes, P. Hande Ozdinler, Mukesh Gautam   +4 more
wiley   +1 more source

Nivolumab-induced Diaphragm Dysfunction: A Case Report. [PDF]

Indian J Crit Care Med, 2023
Schouwenburg JJ.
europepmc   +1 more source