Results 131 to 140 of about 591,105 (206)

Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways. [PDF]

open access: yesBMC Pulm Med, 2023
Shen W   +10 more
europepmc   +1 more source

[Diaphragm dysfunction in patients with chronic obstructive pulmonary disease]

open access: yes, 2003
Contains fulltext : 123539.pdf (Publisher’s version ) (Closed access)Chronic obstructive pulmonary disease (COPD) is characterised by alterations in the airways and lung parenchyma resulting in an increased respiratory workload. Besides
Verheul, A.J., Dekhuijzen, P.N.R.
core  

Sarsasapogenin Preserves Podocyte Integrity and Attenuates Renal Injury in Experimental IgA Nephropathy

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Experimental IgA nephropathy leads to renal inflammation, fibrosis, podocyte injury, and impaired renal function. Sarsasapogenin treatment attenuated inflammatory and profibrotic signaling, reduced extracellular matrix accumulation, preserved nephrin and podocin expression, improved podocyte ultrastructure, and ameliorated renal histopathological ...
Meltem Kumaş   +7 more
wiley   +1 more source

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 33, 4 September 2026.
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney   +5 more
wiley   +1 more source

Persistent Post‐Traumatic Brain Injury Hiccups Unresponsive to Standard Agents: Resolution Associated With Levetiracetam Therapy

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Post‐traumatic hiccups are an uncommon but distressing complication of traumatic brain injury (TBI), often resistant to conventional pharmacological agents, and the underlying mechanism may involve central neurological disruption of inhibitory pathways rather than gastrointestinal or metabolic aetiologies. We report a male patient in his early
Rostom Karajeh   +4 more
wiley   +1 more source

Effects of inspiratory muscle training on exertional breathlessness in patients with unilateral diaphragm dysfunction: a randomised trial. [PDF]

open access: yesERJ Open Res, 2023
Schaeffer MR   +12 more
europepmc   +1 more source

Sintilimab Combined With Albumin‐Bound Paclitaxel and SOX Regimen as Conversion Therapy for Unresectable Advanced Gastric Cancer Achieving Complete Remission: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT For carefully selected patients with unresectable advanced gastric cancer, immunochemotherapy combining PD‐1 inhibitor with albumin‐bound paclitaxel and S‐1/oxaliplatin may achieve deep remission and enable successful R0 resection. Our findings suggest that this multimodal conversion approach could be considered in selected cases with ...
Yufan Tang   +8 more
wiley   +1 more source

Colon Single Stripe Sign in Chronic NSAID Use During Norovirus Infection: A Two‐Hit Model of Ischemic Colitis

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The colon single stripe sign (CSSS) is associated with ischemic‐pattern colonic injury. We report a 69‐year‐old woman with norovirus infection, hematochezia, recurrent left‐sided colitis, and chronic NSAID use found to have CSSS on colonoscopy, suggesting a multifactorial “two‐hit” mechanism involving NSAID‐related mucosal vulnerability and ...
Sushrut Ingawale   +7 more
wiley   +1 more source

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