Results 171 to 180 of about 70,280 (301)

Clinical Impact of Adherence to Fractional Flow Reserve Guidance in Acute Coronary Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Fractional flow reserve (FFR) is established to guide revascularization in stable coronary disease and non‐culprit lesions in acute coronary syndromes (ACS). However, real‐world adherence to FFR guidance across the spectrum of ACS presentations, including ambiguous culprit scenarios, remains incompletely characterized.
Eun Ho Choo, Ik Jun Choi, Sungmin Lim, Donggyu Moon, Dae‐Won Kim, Kiyuk Chang   +5 more
wiley   +1 more source

Echocardiographic Findings in Small-Breed Dogs With Myxomatous Mitral Valve Disease and the Severity of Mitral Regurgitation, Heart Size and Clinical Signs Myxomatous Mitral Valve Disease in Dogs. [PDF]

Vet Med Sci
Elyasi B.
europepmc   +1 more source

Noise‐Blocking Interfacial Lamination of Small‐Molecule Acceptors for Enhanced Signal Clarity in Organic Photodetectors

Carbon Energy, EarlyView.
The structural design strategy employing the Y6‐BO interfacial lamination suppresses dark current by limiting solvent‐induced interfacial damage through the formation of uniformly arranged interfaces while optimizing charge transport to achieve superior detectivity.
Jihyun Lim, Hyunguk Park, Woongsik Jang, Jae Hyun Jeong, Dong Hwan Wang   +4 more
wiley   +1 more source

A Parametric Model of the Mitral Valve for Finite Element Patient-Specific Simulations. [PDF]

Bioengineering (Basel)
Menéndez Hurtado A, Borodinas S.
europepmc   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Correlation between diastolic function and fundus vascular features in coronary heart disease. [PDF]

Int J Ophthalmol
Wang J, Wang YC, Wang L, Li QJ, Jiang J, Wang ZL.   +5 more
europepmc   +1 more source

A ‘fluttering’ diastolic murmur [PDF]

European Heart Journal - Cardiovascular Imaging, 2018
Cameron, Dowling, Sami, Firoozi, Rajan, Sharma, Stephen J, Brecker   +3 more
openaire   +2 more sources

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse, Aliede E. in 't Veld, Hendrika W. Grievink, Manon A.A. Jansen, Matthijs Moerland   +4 more
wiley   +1 more source

Real-world presentation of myocardial bridging in the cath-lab: a case series. [PDF]

Eur Heart J Case Rep
D'Amario D, Vergallo R, Elia S, Rizzo G, Ricchiuto A, Ciliberti G, Porto I, Patti G.   +7 more
europepmc   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source