Results 181 to 190 of about 81,887 (353)

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Cardiorenal Outcomes of Dapagliflozin vs. Empagliflozin in Advanced Chronic Kidney Disease and Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Target trial emulation of a multi‐institutional electronic health record network showed comparable cardiorenal effectiveness and safety of dapagliflozin versus empagliflozin in adults with type 2 diabetes and advanced‐stage chronic kidney disease.
Shih‐Hsuan Lin, Jia‐Jin Chen, Ching‐Chung Hsiao, Yu‐Wei Fang, Meng‐Ting Chen, Ming‐Hsien Tsai, Huang‐Yu Yang   +6 more
wiley   +1 more source

Developing a calibration method to utilize low-dose chest CT for assessment of coronary artery calcification score. [PDF]

J Appl Clin Med Phys
Hou KY, Yang CC.
europepmc   +1 more source

<p>Association Between Adherence To The French Dietary Guidelines And Lower Resting Heart Rate, Longer Diastole Duration, And Lower Myocardial Oxygen Consumption. The NUTRIVASC Study</p>

, 2019
M. Fysekidis, Emmanuelle Kesse‐Guyot, Paul Valensi, Nathalie Arnault, Pilar Galán, Serge Herçberg, Emmanuel Cosson   +6 more
openalex   +2 more sources

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Phase-targeting rapid cryofixation of the beating heart and histological analysis unveil contractile state-dependent sarcomere dynamics. [PDF]

Sci Rep
Tamura S, Mochizuki K, Kumamoto Y, Morishita Y, Yamanaka M, Ho WJ, Harada Y, Fujita K, Tanaka H.   +8 more
europepmc   +1 more source

A novel flow waveform partitioning method based on the HeartCon and its clinical application. [PDF]

Front Cardiovasc Med
Wang H, Lin G, Han Z, Liu X.
europepmc   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

Deep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu, Dawei Cui, Yingjie Liu, Yuntao Liang, Yue Zhang   +4 more
wiley   +1 more source

[Diastolic heart failure].

Der Internist, 2015
Heart failure with preserved ejection fraction (i.e. diastolic heart failure) accounts for about half of heart failure cases. The aim of this review is to reflect current knowledge regarding the epidemiology, pathophysiology and treatment.Diastolic heart failure patients are principally elderly and predominantly female.
openaire   +2 more sources

An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine. [PDF]

JACC Case Rep
Stark AW, Mokhtari A, Kakizaki R, Bigler MR, Siepe M, Shiri I, Räber L, Gräni C.   +7 more
europepmc   +1 more source