Results 201 to 210 of about 114,320 (373)

A class of directed acyclic graphs with mixed data types in mediation analysis

Canadian Journal of Statistics, EarlyView.
Abstract We propose a unified class of generalized structural equation models (GSEMs) with data of mixed types in mediation analysis, including continuous, categorical, and count variables. Such models extend substantially the classical linear structural equation model to accommodate many data types arising from the application of mediation analysis ...
Wei Hao, Canyi Chen, Peter X.‐K. Song
wiley   +1 more source

Reliability of comprehensive echocardiography evaluation of patent ductus arteriosus among extremely preterm neonates across a national network: A prospective observational study. [PDF]

J Neonatal Perinatal Med
Weisz DE, Thomas L, Ye XY, Mertens L, Lapointe A, Villeneuve A, Altit G, Lalitha R, Ben Fadel N, Jacob G, Louis D, Bhattacharya S, Soraisham A, Hébert A, Mitra S, Hyderi A, Ting JY, Castaldo M, Surak A, Deshpande P, Elsayed Y, Jasani B, Nissimov S, Zhu F, Shah P, Jain A.   +25 more
europepmc   +1 more source

429 Computational Mechanical Modeling of LV Blood Dynamics with Consideration of Realistic Shape, Open and Closure of Valves, and Systole-Diastole-Function

, 2006
Hisashi Taniguchi, Fuyou Liang, Shinichi Fujimoto, Ryutaro Himeno, Hao Liu   +4 more
openalex   +2 more sources

Pharmacokinetics and Bioequivalence of a Novel Extended‐Release Formulation of Methylphenidate Hydrochloride for Attention‐Deficit/Hyperactivity Disorder

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Extended‐release (ER) formulations of the stimulant methylphenidate are commonly used to treat attention‐deficit/hyperactivity disorder in both children and adults. Previous studies have shown that the clinical effectiveness of long‐acting methylphenidate formulations is closely tied to the drug's pharmacokinetic (PK) profile, highlighting the
Ann C. Childress, Ahmad AL‐Sabbagh, Jeffrey H. Newcorn   +2 more
wiley   +1 more source

Influence of Signalment Variables on Body Weight-Normalized Echocardiographic Measurements of Heart Size in 56 169 Adult Unsedated Normal Pure-Bred Cats. [PDF]

J Vet Intern Med
Häggström J, Ohlsson Å, Falk T, Wess G, Friederich J, Olsson U, Nilsfors L, Kresken JG, Högström K, Beijerink N, Rishniw M, Tidholm A, Ljungvall I.   +12 more
europepmc   +1 more source

Renal denervation in heart failure with normal left ventricular ejection fraction. Rationale and design of the DIASTOLE (DenervatIon of the renAl Sympathetic nerves in hearT failure with nOrmal Lv Ejection fraction) trial

European Journal of Heart Failure, 2013
Willemien L. Verloop, Martine M. A. Beeftink, A. Nap, M. Bots, B. Velthuis, Y. Appelman, M. Cramer, W. Agema, A. Scholtens, P. Doevendans, C. Allaart, M. Voskuil   +11 more
semanticscholar   +1 more source

Safety and Efficacy of the NMDA‐2b‐Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder

Clinical Pharmacology &Therapeutics, EarlyView.
Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre, Gerard Sanacora, David P. Walling, Elan A. Cohen, Shishuka Malhotra, Holger Rosenbrock, Manuela Schmitz, Andreas Scholz, Sigurd D. Süssmuth, Franco De Crescenzo   +9 more
wiley   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source

Effect of position of body on the length of systole and diastole and rate of pulse in man [PDF]

, 1919
W. P. Lombard, Otis M. Cope
openalex   +1 more source

STUDIES ON THE CONSECUTIVE PHASES OF THE CARDIAC CYCLE: II. The Laws Governing the Relative Durations of Ventricular Systole and Diastole

, 1921
C. Wiggers
semanticscholar   +1 more source