Results 21 to 30 of about 114,320 (373)

Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (−)‐noradrenaline

Pharmacology Research & Perspectives, 2021
Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifically ...
Alexander Dashwood, Elizabeth Cheesman, Yee Weng Wong, Haris Haqqani, Nicole Beard, Karen Hay, Melanie Spratt, Wandy Chan, Peter Molenaar   +8 more
doaj   +1 more source

Numerical study of hemodynamics after stent implantation during the cardiac cycle

Journal of Mechanical Engineering and Sciences, 2021
The descending aortic aneurysm is one of the most catastrophic cardiovascular emergencies resulting in high mortality worldwide. Clinical observations have pointed out that stent implantation in the sick aorta should probably allow stabilization of the ...
A. Belaghit, B. Aour, M. Larabi, A. A. Tadjeddine, S. Mebarki   +4 more
doaj   +1 more source

Early diastolic filling dynamics in diastolic dysfunction [PDF]

Cardiovascular Ultrasound, 2003
The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction.The relationship between early passive diastolic transmitral flow and peak early mitral annular ...
Gerard King, Michael Walsh, Faisal Almane, J B Foley, Peter A. Crean   +4 more
openaire   +4 more sources

Diastolic and Systolic Longitudinal Myocardial Velocities of Healthy Racing Pigeons (Columba livia f. domestica) Measured by Tissue Doppler Imaging

Veterinary Sciences, 2021
Tissue Doppler imaging (TDI) is a noninvasive sonographic method of acquiring and quantifying myocardial velocities. This technique is used in human and small animal medicine to diagnose cardiac diseases.
Marko Legler, Lajos Koy, Norbert Kummerfeld, Michael Fehr   +3 more
doaj   +1 more source

Measuring left ventricular volumes in two-dimensional echocardiography image sequence using level-set method for automatic detection of end-diastole and end-systole frames

Research in Cardiovascular Medicine, 2012
Background: Identifying End-Diastole (ED) and End-Systole (ES) frames is highly important in the process of evaluating cardiac function and measuring global parameters accurately, such as Ejection Fraction (EF), Cardiac Output (CO) and Stroke Volume ...
Saeed Darvishi, Hamid Behnam, Majid Pouladian, Niloufar Samiei   +3 more
openalex   +2 more sources

Diastolic heart failure [PDF]

Cardiovascular Research, 2000
Primary diastolic failure is typically seen in patients with hypertensive or valvular heart disease as well as in hypertrophic or restrictive cardiomyopathy but can also occur in a variety of clinical disorders, especially tachycardia and ischemia. Diastolic dysfunction has a particularly high prevalence in elderly patients and is generally associated,
Mandinov, Lazar, Eberli, Franz R., Seiler, Christian, Hess, Otto M.   +3 more
openaire   +7 more sources

The impact of cardiac loading on a novel metric of left ventricular diastolic function in healthy middle‐aged adults: Systolic–diastolic coupling

Physiological Reports, 2021
Aims Left ventricular (LV) restoring forces are primed by ventricular deformation during systole and contribute to cardiac relaxation and early diastolic suction.
James P. MacNamara, Vivek Koshti, Katrin A. Dias, Erin Howden, Christopher M. Hearon Jr, I‐Jou Cheng, Linda S. Hynan, Benjamin D. Levine, Satyam Sarma   +8 more
doaj   +1 more source

Falla cardiaca con fracción de eyección preservada: un problema de la cardiología contemporánea

Archivos Peruanos de Cardiología y Cirugía Cardiovascular, 2020
La falla cardíaca con fracción de eyección preservada (FCFep) constituye una entidad frecuente, sub- diagnosticada, que implica un gran reto diagnóstico y terapéutico.
Clara Saldarriaga-Giraldo, Cristhian Felipe Ramirez Ramos, Catalina Gallego, Gustavo Castilla-Agudelo, Mateo Aranzazu-Uribe, Santiago Saldarriaga-Betancur   +5 more
doaj   +1 more source

CLINICAL ROLE OF CRITICAL CARE ECHOCARDIOGRAPHY IN SEPTIC PATIENTS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS [PDF]

Euromediterranean Biomedical Journal, 2020
Critical care echocardiography (CCE) use is rapidly growing and echocardiography is recommended as first-line approach to patients presenting with shock.
Cristina Santonocito
doaj   +1 more source

Differences between the Filling Velocities of the Left and Right Heart Ventricle in Racing Pigeons (Columba livia F. Domestica) and the Influence of Anesthesia with Isoflurane

Veterinary Sciences, 2019
The ventricular filling velocities during diastole and the influence of isoflurane anesthesia on these blood flow velocities of the racing pigeon (n = 43) are evaluated by pulsed-wave (PW) Doppler sonography. Sonographic examination demonstrates an early
Marko Legler, Lajos Koy, Norbert Kummerfeld, Michael Fehr   +3 more
doaj   +1 more source