Results 21 to 30 of about 71,564 (304)
Pharmacology Research & Perspectives, 2021 Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifically ...
Alexander Dashwood +8 more
doaj +1 more source
Adiponectin Deficiency, Diastolic Dysfunction, and Diastolic Heart Failure [PDF]
Endocrinology, 2010 Abstract Aldosterone infusion results in left ventricular hypertrophy (LVH) and hypertension and may involve profibrotic and proinflammatory mechanisms. In turn, hypertension is the major cause of diastolic heart failure (HF). Adiponectin, an adipose-derived plasma protein, exerts antiinflammatory and anti-hypertrophic effects and is ...
Flora, Sam +10 more
openaire +2 more sources
Left ventricular T1-mapping in diastole versus systole in patients with mitral regurgitation [PDF]
, 2022 Cardiovascular magnetic resonance T1-mapping enables myocardial tissue characterisation, and is capable of quantifying both intracellular and extracellular volume. T1-mapping is conventionally performed in diastole, however, we hypothesised that systolic
Liu, Boyang +9 more
core +1 more source
Dose Impaired Relaxation of Left Ventricle Affect Early Outcomes [PDF]
Acta Medica Iranica, 2010 Although systolic dysfunction is revealed as a prognostic factor in cardiac surgery , the role of diastolic dysfunction as a predictive factor is less evaluated. In this retrospective study from 872 patients that underwent isolated coronary artery bypass
Jamshid Bagheri, Fereshteh Rezakhanloo
doaj +1 more source
Diastolic dysfunction in hypertension
Hipertensión y Riesgo Vascular, 2017 Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic.
Nazário Leão, R, Marques da Silva, P
openaire +3 more sources
Aortic valve stenosis: Prognosis and therapy [PDF]
Vojnosanitetski Pregled, 2003 There is a long latent period in the clinical course of aortic valve stenosis in adults. Symptoms usually occur in the case of critical stenosis, when aortic orifice area is under 0.7cm2 (0.4 cm2/m2).
Ristić-Anđelkov Anđelka +5 more
doaj +1 more source
Diagnostics, 2023 This pilot study aimed to develop a new, reliable, and easy-to-use method for the evaluation of diastolic function through the M-mode measurement of mitral valve (MV) movement in the parasternal long axis (PSLA), similar to E-point septal separation ...
Chan-Ho Park +12 more
doaj +1 more source
Diastolic dysfunction types in the prediction of viable myocardium functional recovery [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. It is well known that patients with coronary artery disease and viable tissue as a guarantee of contractile recovery (CR), despite of decreasing ejection fraction (EF) and systolic dysfunction, could have benefit from surgical ...
Matunović Radomir +4 more
doaj +1 more source
Ueber die locale Diastole des Herzens
, 1882 UEBER DIE LOCALE DIASTOLE DES HERZENS Ueber die locale Diastole des Herzens (28) (-
Luchsinger, Balthasar
core +2 more sources
Medicina, 2023 Background and Objectives: Cardiovascular magnetic resonance (CMR) is emerging as an important imaging tool for sub-phenotyping and estimating left ventricular (LV) filling pressure (LVFP).
Hosamadin Assadi +7 more
doaj +1 more source