Results 61 to 70 of about 66,989 (314)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Coronary input impedance is constant during systole and diastole [PDF]
, 1991 Although it is well known that coronary inflow decreases substantially during systole, the mechanism responsible for this decrease remains controversial. Knowledge of how coronary input impedance is affected by contraction can differentiate between some
R. M. Judd, R. E. Mates
core +1 more source
Arthritis Care &Research, EarlyView.Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source
Hydrodynamics of Cardiac Diastole [PDF]
, 2011 Left ventricular diastole (filling) is a complex process with many features and coupled compensatory mechanisms which coordinate to maintain optimal filling and ejection of the left ventricle.
Stewart, Kelley Christine
core
GWAS summary statistics for left-ventricular phenotypes at end-diastole [PDF]
<h2>GWAS summary statistics for left-ventricular traits at end-diastole</h2> <p>These phenotypes were derived from 3D meshes of the left ventricle at end-diastole, which in turn were obtained via segmentation from cardiovascular ...
Bonazzola, Rodrigo
core +1 more source
Stress Distribution in the Canine Left Ventricle during Diastole and Systole [PDF]
, 1970 A model is proposed for stress analysis of the left ventricular wall (LV wall) based on the realistic assumption that the myocardium is essentially composed of fiber elements which carry only axial tension and vary in orientation through the wall. Stress
Sonnenblick, Edmund H. +5 more
core +1 more source
NO and cardiac diastolic function [PDF]
Cardiovascular Research, 1999 Time for primary review 34 days. Since the first report of a role for nitric oxide (NO) in modulating myocardial contractile function in 1991 [1], an enormous number of studies have been published in this field (recently reviewed in Refs. [2–4]). It is now recognised that, under physiological conditions, the major sources of NO that are important for
W J, Paulus, A M, Shah
openaire +2 more sources
Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Arthritis Care &Research, EarlyView.Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source