Results 111 to 120 of about 4,571,560 (259)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

“Zero” diastolic blood pressure

The Indian Anaesthetists' Forum, 2016
Deepak Choudhary, Om Prakash Suthar, Pradeep Kumar Bhatia, Ghansham Biyani   +3 more
doaj   +1 more source

Blood pressure responses during walking in water in middle-aged and elderly women [PDF]

, 2007
The purpose of this study was to investigate the effectiveness of physical activity in water from the perspective of blood pressure responses in middle-aged and elderly women for whom water exercise is recommended.
ウエダ, タケシ, イシハラ, カズナリ, オオガキ, テツロウ, 石原, 一成, 正野, 友基, SHONO, Tomoki, ショウノ, トモキ, HOTTA, Noboru, 大柿, 哲郎, 761, 762, 763, ISHIHARA, Kazunari, 上田, 毅, UEDA, Takeshi, 堀田, 昇, ホッタ, ノボル, OGAKI, Tetsuro, 707, 708   +19 more
core  

Lowering salivary pH with sugar‐containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice)

British Journal of Clinical Pharmacology, EarlyView.
Acutely lowering salivary pH (with sugar‐containing acidic gum vs. sugar‐free gum) augments salivary nitrate reduction to nitrite, plasma nitrite concentration, and blood pressure lowering with dietary nitrate. Modifying salivary pH reveals a mechanism by which the nitrate‐nitrite‐NO pathway may be upregulated/inhibited, with potential for other ...
Andrew J. Webb, Harriet Clift, Callum Hill, Nur Mousa, Navanithan Arun Jayaraj, Jasmine Quraishi, Charlotte E. Mills, Kevin O'Gallagher   +7 more
wiley   +1 more source

Relationship of dietary linoleic acid to blood pressure: the international study of macro-micronutrients and blood pressure study

, 2008
Findings from observational and interventional studies on the relationship of dietary linoleic acid, the main dietary polyunsaturated fatty acid, with blood pressure have been inconsistent.
Rodriguez, B.L., Miura, K., Saitoh, S., Curb, J.D., Ueshima, H., Elliott, P., Okayama, A., Tzoulaki, I., Robertson, C.E., Dyer, A.R., Daviglus, M.L., Stamler, J., Elmer, P.J., Brown, I.J., Zhao, L., Chan, Q., Kesteloot, H., Nakagawa, H., Steffen, L.M.   +18 more
core   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Blood pressure levels among the studentsof a selected school

IMC Journal of Medical Science, 2010
In Bangladesh, limited data are available on paediatric hypertension as well as their normal values. This study was done to assess the level of blood pressure in this population group.
Abdullah Al-Shafi Mazumder, Meerjady Sabrina Flora, Md. Shahidullah, Rokeya Khanam, Md. Abdur Rashid, Md. Hasan Iqbal   +5 more
doaj  

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source